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Idiopathic hypereosinophilic syndrome (HES) is a rare leukoproliferative systemic disorder characterized by sustained overproduction of eosinophils and poor prognosis. A case that a 67-year-old man with persistent symptoms of heart failure due to cardiac involvement in idiopathic HES is concentrated on. Echocardiography revealed the marked endocardial(More)
The C domain of eRF1 interacts with the C domain of eRF3, and the binding of both factors is essential for fast kinetics of the termination of protein translation. Analysis by computational simulation demonstrated that several peptides involved in Eo-eRF1/Eo-eRF3 interaction directly. Among these peptides, the two motifs GVEDT and GFGG were highly(More)
本文介绍一例以胸痛、呼吸困难为主要表现, 反 复发生非心源性肺水肿、持续性低血压和急性冠 脉综合征的囊性嗜铬细胞瘤患者。囊性嗜铬细胞 瘤合并多种严重并发症临床上少有报道, 容易误 诊和漏诊。对于出现肺水肿、持续性低血压和急 性冠脉综合征等严重体征, 临床诊断又不明确的 患者, 需要考虑嗜铬细胞瘤的可能。
The binding of both factors (eRF1 and eRF3) is essential for fast kinetics of the termination of protein translation. The C-terminal domain of eRF1 is known to interact with the C domain of eRF3. Eo-eRF1b contains two highly conserved tryptophan residues (W-11 and W-373), W-11 located in the Eo-eRF1b N domain and W-373 located in the EoeRF1b C domain.(More)
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