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Characterization of the human heart mitochondrial proteome
An extensive catalogue of the mitochondrial proteome using highly purified mitochondria from normal human heart tissue and subsequent detection by mass spectrometry and rigorous bioinformatic analysis yielded 615 distinct protein identifications.
Detecting differential and correlated protein expression in label-free shotgun proteomics.
- Bing Zhang, N. Verberkmoes, M. Langston, E. Uberbacher, R. Hettich, N. Samatova
- BiologyJournal of proteome research
- 11 October 2006
A systematic analysis of various approaches to quantifying differential protein expression in eukaryotic Saccharomyces cerevisiae and prokaryotic Rhodopseudomonas palustris label-free LC-MS/MS data demonstrated that proteins co-located in the same operon were much more strongly coexpressed than those from different operons.
Characterization of early, chitin-induced gene expression in Arabidopsis.
- Bing Zhang, K. Ramonell, S. Somerville, G. Stacey
- BiologyMolecular plant-microbe interactions : MPMI
- 1 September 2002
The level of chitin-induced gene expression of the lectin-like protein and AtMPK3 was not significantly changed in mutants blocked in the jasmonic acid (JA, jar1)-, ethylene (ein2)-, or salicylic acid (SA, pad4, npr1, and eds5)-dependent pathway, and expression of mRNA for the zinc finger protein was reduced in the mutants affected in the JA- or SA-dependent pathway.
Oxidative Damage to Mitochondrial Complex I Due to Peroxynitrite
- J. Murray, Steven W. Taylor, Bing Zhang, Soumitra S Ghosh, R. Capaldi
- Biology, ChemistryJournal of Biological Chemistry
- 26 September 2003
It is shown that peroxynitrite reacts with mitochondrial membranes from bovine heart to significantly inhibit the activities of complexes I, II, and V but with less effect upon complex IV and no significant inhibition of complex III.
The Small Heat Shock Protein ODF1/HSPB10 Is Essential for Tight Linkage of Sperm Head to Tail and Male Fertility in Mice
- Kefei Yang, A. Meinhardt, Bing Zhang, P. Grzmil, I. Adham, S. Hoyer-Fender
- BiologyMolecular and Cellular Biology
- 28 October 2011
The results suggest that ODF1, besides being involved in the correct arrangement of mitochondrial sheath and outer dense fibers, is essential for rigid junction of sperm head and tail, and might account for some of the cases of human infertility with decapitated sperm heads.
Arabidopsis AtbHLH112 regulates the expression of genes involved in abiotic stress tolerance by binding to their E-box and GCG-box motifs.
A model is presented suggesting that AtbHLH112 is a transcriptional activator that regulates the expression of genes via binding to their GCG- or E-boxes to mediate physiological responses, including proline biosynthesis and ROS scavenging pathways, to enhance stress tolerance.
Characterization of Anaerobic Catabolism of p-Coumarate in Rhodopseudomonas palustris by Integrating Transcriptomics and Quantitative Proteomics*S
The integrated gene expression data provided strong support for the non-β-oxidation route in R. palustris, consistent with the hypothesis that p-coumarate is converted to benzoyl-CoA, which is then degraded via a known aromatic ring reduction pathway.
Manganese scavenging and oxidative stress response mediated by type VI secretion system in Burkholderia thailandensis
- Meiru Si, Chao Zhao, Xihui Shen
- BiologyProceedings of the National Academy of Sciences
- 27 February 2017
The contact-independent functions of T6 SS for metal acquisition and bacteria–bacteria competition, reported here, suggest that T6SS may have been retrofitted by some bacteria to gain additional adaptive functions during evolution and provide a perspective for understanding the mechanisms of metal ion uptake and the roles of T 6SS in bacteria– bacteria competition.
The Type VI Secretion System Engages a Redox-Regulated Dual-Functional Heme Transporter for Zinc Acquisition.
The Subunit Composition of the Human NADH Dehydrogenase Obtained by Rapid One-step Immunopurification*
Using small amounts of immunoisolated protein, one-dimensional and two-dimensional gel electrophoresis, matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF), and peptide mass finger printing (PMF), the human homologues of 42 polypeptides detected so far in beef heart complex I can be identified.