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TR3, an immediate-early response gene and an orphan member of the steroid-thyroid hormone-retinoid receptor superfamily of transcription factors, regulates apoptosis through an unknown mechanism. In response to apoptotic stimuli, TR3 translocates from the nucleus to mitochondria to induce cytochrome c release and apoptosis. Mitochondrial targeting of TR3,(More)
We compare the maximal two-photon fluorescence microscopy (TPM) imaging depth achieved with 775-nm excitation to that achieved with 1280-nm excitation through in vivo and ex vivo TPM of fluorescently-labeled blood vessels in mouse brain. We achieved high contrast imaging of blood vessels at approximately twice the depth with 1280-nm excitation as with(More)
Recent experimental investigations have emphasized the importance of assessing both acute and chronic histopathological changes occurring after cerebral ischemia. The purpose of this study was to evaluate the temporal profile of neuronal, astrocytic and microglial alterations within vulnerable regions (striatum and CA1 sector of hippocampus) following(More)
The purpose of this investigation was to investigate pathomechanisms responsible for the deleterious effects of repeated episodes of brief forebrain ischemia. Halothane-anesthetized male Wistar rats were subjected to either (a) a single 15-min period or (b) three 5-min periods (separated by 1 h) of global forebrain ischemia by bilateral carotid artery(More)
Land surface microwave emissivities are important geophysical parameters for atmospheric, hydrological, and biospheric studies. This study estimates land surface microwave emissivity using an atmospheric microwave radiative transfer model and a combination of the Special Sensor Microwave/Imager (SSM/I) satellite observations and data from the Atmospheric(More)
BACKGROUND Potential functional allele A/T single nucleotide polymorphism (SNP) of Interleukin 8 (IL-8) promoter -251 has been implicated in gastric cancer risk. METHODS We aimed to explore the role of A/T SNP of IL-8 -251 in the susceptibility to gastric cancer through a systematic review and meta-analysis. Each initially included article was scored for(More)
yet despite many improvements, large differences in retrievals of their liquid water amount and particle size still must be resolved. C louds play a critical role in modulating the radia-tive transfer in the atmosphere, and the way in which clouds interact with the atmosphere and impact the Earth's radiative energy balance is one of the primary(More)
Potential functional allele T/C single nucleotide polymorphism (SNP) of Interleukin 10 (IL-10) promoter -819 (rs1800871) has been implicated in gastric cancer risk. We aimed to explore the role of T/C SNP of IL-10 -819 in the susceptibility to gastric cancer through a systematic review and meta-analysis. Each initially included article was scored for(More)
Cloud properties were retrieved by applying the Clouds and Earth's Radiant Energy System (CERES) project Edition-2 algorithms to 3.5 years of Tropical Rainfall Measuring Mission Visible and Infrared Scanner data and 5.5 and 8 years of MODerate Resolution Imaging Spectroradiometer (MODIS) data from Aqua and Terra, respectively. The cloud products are(More)
A technique we refer to as Elevation Information in Tail (EIT) has been developed to provide improved lidar altimetry from CALIPSO lidar data. The EIT technique is demonstrated using CALIPSO data and is applicable to other similar lidar systems with low-pass filters. The technique relies on an observed relation between the shape of the surface return(More)