Skip to search formSkip to main contentSkip to account menu
Establishment of High-Performance Liquid Chromatography and Enzyme Multiplied Immunoassay Technology Methods for Determination of Free Mycophenolic Acid and Its Application in Chinese Liver…
TLDR
A considerable interindividual variability exists in pharmacokinetics of fMPA among Chinese liver transplant recipients and 7-O-Glucuronide conjugate of MPA and albumin concentrations are two factors correlated to fM PA variance.
View on Wolters Kluwer
Population pharmacokinetic study of cyclosporine in Chinese renal transplant recipients
TLDR
The PPK model developed in this study could be used to optimize CsA dose for Chinese renal transplant recipients by using conventional therapeutic drug monitoring (TDM) data.
View on Springer
Clinical pharmacy service practice in a Chinese tertiary hospital
TLDR
The working model of clinical pharmacists in a Chinese tertiary hospital is introduced, including ward rounds, consultation, stewardship of antimicrobial therapy, drug adverse reaction monitoring, therapeutic drug monitoring, clinical pharmacokinetics and pharmacogenetics, and training system.
View on PubMed
Influence of CYP2D6*10B genotype on pharmacokinetics of propafenone enantiomers in Chinese subjects.
  • Bing Chen, W. Cai
  • Chemistry, Biology
    Acta pharmacologica Sinica
  • 1 December 2003
TLDR
CYP2D 6*10B alleles induce the declined activity of CYP2D6 and impair the metabolism of propafenone, and the CL of both enantiomers in *10/*10 is only half of that of *1*/10 group or *1/*1 group (P<0.05).
View on PubMed
Models for the prediction of mycophenolic acid area under the curve using a limited-sampling strategy and an enzyme multiplied immunoassay technique in Chinese patients undergoing liver…
View on PubMed
Population Pharmacokinetics and Bayesian Estimation of Mycophenolic Acid Exposure in Chinese Renal Allograft Recipients After Administration of EC‐MPS
TLDR
The PPK model was acceptable and can describe the pharmacokinetics of MPA in Chinese renal transplant recipients administered EC‐MPS and could be estimated through a limited sampling strategy method, based on which individualized immunosuppressive regimens could be designed.
View on Wiley
Population pharmacokinetic analysis of intravenous busulfan: GSTA1 genotype is not a predictive factor of initial dose in Chinese adult patients undergoing hematopoietic stem cell transplantation
TLDR
The GSTA1 genotype-based PPK model of intravenous busulfan was successfully developed and externally validated and the GSTA 1 genotype was not considered to be clinically relevant to busulfa CL, so it did not suggest the guidance of GSTA2 genotype on initial busulfans dose in Chinese adult patients.
View on Springer
A Validation Study on eGFR Equations in Chinese Patients With Diabetic or Non-diabetic CKD
TLDR
This study showed that eGFR equations were less accurate in the diabetic group than in the non-diabetic group, and CKD-EPIScr−CysC had the best performance among CKd-EPI equations in Chinese diabetic CKD patients.
View on PubMed
Accurate Prediction of Initial Busulfan Exposure Using a Test Dose With 2‐ and 6‐Hour Blood Sampling in Adult Patients Receiving a Twice‐Daily Intravenous Busulfan‐Based Conditioning Regimen
TLDR
A test dose with a 2‐sampling scheme was sufficient to personalize the initial busulfan dosing in hematopoietic cell transplant recipients, and the Bland‐Altman plot showed that the 2‐Sampling scheme provided an acceptably accurate prediction of the AUC1.
View on Wiley
Clinical mycophenolic acid monitoring in liver transplant recipients.
TLDR
The published data suggested that a fixed-dosage MMF regimen might not be suitable and monitoring of MPA exposure seems helpful in various clinical settings of liver transplantation, and the value of clinical use needs to be investigated in future.
View PDF
...
...
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License