Binbin Gong

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MicroRNAs (miRNAs) are small non-coding RNAs that function as endogenous silencers of target genes, previous studies have shown that miR-335 play an important role in suppressing metastasis and migration in human cancer including gastric cancer (GC). However, the mechanisms which result in aberrant expression of miR-335 in GC are still unknown. Recent(More)
Altered expression of paxillin (PXN) is closely linked to the pathogenesis progression, metastasis and prognosis of different malignancies including gastric cancer (GC). Epigenetic silencing of tumor-suppressive microRNAs (miRNAs) is a crucial component of the mechanism underlying activation of oncogenes in tumor. To screen for epigenetically silenced(More)
Erectile dysfunction (ED) is a major care problem worldwide. Tadalafil and sildenafil are the two most common phosphodiesterase 5 inhibitors used to treat ED. This systematic review and meta-analysis were conducted to directly compare tadalafil with sildenafil for the treatment of ED. We designed a strategy for searching the PubMed, Embase, EBSCO, Web of(More)
Background: To compare the efficacy and safety of transurethral PlasmaKinetic enucleation of prostate (PKEP) versus transurethral PlasmaKinetic resection of prostate (PKRP) for benign prostate hyperplasia. Methods: The Prospective and randomized controlled trials (RCTs) pertaining to PKEP and PKRP for benign prostate hyperplasia were retrieved from PubMed,(More)
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