Binara Amarasinghe

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Familial Adenomatous Polyposis (FAP) is an autosomal dominant condition giving rise to multiple adenomatous polyps in the colon which invariably become malignant by the fourth decade. Congenital hypertrophy of retinal pigment epithelium (CHRPE) is one of its extra intestinal manifestations early in childhood seen, present in 90% of FAP population and is(More)
A 41-year old previously healthy woman presented with severe headache, vomiting, low grade fever, bilateral eye pain, photophobia and deteriorating vision over one week. Examination showed neck stiffness and bilateral papilloedema [Figures 1 and 2]. She had no evidence of autoimmune disorders. Contrast CT brain and routine investigations were normal. CSF(More)
OBJECTIVES To improve the prognosis of patients with familial adenomatous polyposis (FAP) by early diagnosis and prophylactic treatment through a coordinated FAP register. DESIGN The establishment and descriptive analysis of the prospective database of the FAP registry. SETTING University surgical unit, Colombo North Teaching Hospital Ragama, Sri Lanka.(More)
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