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The Panasas file system uses parallel and redundant access to object storage devices (OSDs), per-file RAID, distributed metadata management, consistent client caching, file locking services, and internal cluster management to provide a scalable, fault tolerant, high performance distributed file system. The clustered design of the storage system and the use(More)
Device-to-device (D2D) communications help improve the performance of wireless multicast services in cellular networks via cooperative retransmissions among multicast recipients within a cluster. Resource utilization efficiency should be taken into account in the design of D2D communication systems. To maximize resource efficiency of D2D retransmissions,(More)
Motivated by the superlinear behavior of the Barzilai-Borwein (BB) method for two-dimensional quadratics, we propose two gradient methods which adaptively choose a small step-size or a large step-size at each iteration. The small step-size is primarily used to induce a favorable descent direction for the next iteration, while the large step-size is(More)
In animals, steroid hormones play critical roles in many vital physiological processes. Brassinosteroids (BRs) produced by plants have similar structures to the animal steroid hormones and play indispensable roles in plant growth and development [1]. BRs have now ac-knowledgedly become a sixth class of plant hormones. In contrast to animal steroid hormones(More)
The synthesis of adiponectin, an adipokine with ill-defined functions in animals fed a normal diet, is enhanced by the osteoblast-derived hormone osteocalcin. Here we show that adiponectin signals back in osteoblasts to hamper their proliferation and favor their apoptosis, altogether decreasing bone mass and circulating osteocalcin levels. Adiponectin(More)
A screen of microRNAs preferentially expressed in osteoblasts identified members of the miR-34 family as regulators of osteoblast proliferation and/or differentiation. Osteoblast-specific gain- and loss-of-function experiments performed in vivo revealed that miR-34b and -c affected skeletogenesis during embryonic development, as well as bone mass accrual(More)
A fundamental problem in systems biology and whole genome sequence analysis is how to infer functions for the many uncharacterized proteins that are identified, whether they are conserved across organisms of different phyla or are phylum-specific. This problem is especially acute in pathogens, such as malaria parasites, where genetic and biochemical(More)
This paper presents optimized implementations of two different pipeline FFT processors on Xilinx Spartan-3 and Virtex-4 FPGAs. Different optimization techniques and rounding schemes were explored. The implementation results achieved better performance with lower resource usage than prior art. The 16-bit 1024-point FFT with the R22SDF architecture had(More)
Algebraic testing is an automated software testing method based on algebraic formal specifications. It has the advantages of highly automated testing process and independence of the software's implementation details. This paper applies the method to software components. An automated testing tool called CASCAT for Java components is presented. A case study(More)