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As industry moves towards many-core chips, networks-on-chip (NoCs) are emerging as the scalable fabric for interconnecting the cores. With power now the first-order design constraint, early-stage estimation of NoC power has become crucially important. ORION [29] was amongst the first NoC power models released, and has since been fairly widely used for(More)
The sparsity problem in collaborative filtering (CF) is a major bottleneck for most CF methods. In this paper, we consider a novel approach for alleviating the sparsity problem in CF by transferring useritem rating patterns from a dense auxiliary rating matrix in other domains (e.g., a popular movie rating website) to a sparse rating matrix in a target(More)
Cross-domain collaborative filtering solves the sparsity problem by transferring rating knowledge across multiple domains. In this paper, we propose a rating-matrix generative model (RMGM) for effective cross-domain collaborative filtering. We first show that the relatedness across multiple rating matrices can be established by finding a shared implicit(More)
Just as neuronal activity is essential to normal brain function, microtubule-associated protein tau appears to be critical to normal neuronal activity in the mammalian brain, especially in the evolutionary most advanced species, the homo sapiens. While the loss of functional tau can be compensated by the other two neuronal microtubule-associated proteins,(More)
We describe the genome sequencing of an anonymous individual of African origin using a novel ligation-based sequencing assay that enables a unique form of error correction that improves the raw accuracy of the aligned reads to >99.9%, allowing us to accurately call SNPs with as few as two reads per allele. We collected several billion mate-paired reads(More)
The innate immune system is absolutely required for host defence, but, uncontrolled, it leads to inflammatory disease. This control is mediated, in part, by cytokines that are secreted by macrophages. Immune regulation is extraordinarily complex, and can be best investigated with systems approaches (that is, using computational tools to predict regulatory(More)
Interference alignment (IA) has evolved as a powerful technique in the information theoretic framework for achieving the optimal degrees of freedom of interference channel. In practical systems, the design of specific interference alignment schemes is subject to various criteria and constraints. In this paper, we propose novel transceiver schemes for the(More)
Abnormal sphingolipid metabolism has been previously reported in Alzheimer's disease (AD). To extend these findings, several sphingolipids and sphingolipid hydrolases were analyzed in brain samples from AD patients and age-matched normal individuals. We found a pattern of elevated acid sphingomyelinase (ASM) and acid ceramidase (AC) expression in AD,(More)
BitTorrent, the immensely popular file swarming system, suffers a fundamental problem: unavailability. Although swarming scales well to tolerate flash crowds for popular content, it is less useful for unpopular or rare files as peers arriving after the initial rush find the content unavailable. Our primary contribution is a model to quantify content(More)
A well defined cost function is crucial to steganography under the scenario of minimizing embedding distortion. In this paper, we present a new cost function for spatial image steganography. The proposed cost function is designed by using a high-pass filter to locate the less predictable parts in an image, and then using two low-pass filters to make the low(More)