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Co og gn ni it ti iv ve e a an nd d U Us sa ab bi il li it ty y I Is ss su ue es s i in n G Ge eo ov vi is su ua al li iz za at ti io on n ABSTRACT: We provide a research agenda for the International Cartographic Association's Commission on Visualization and Virtual Environment working group on Cognitive and Usability Issues in Geovisualization.(More)
Visual deprivation affects the responses of layer IV cells more prominently during early postnatal development, whereas responses in layer II/III remain modifiable until later ages. We examined whether these laminar differences correlate with changes in long-term potentiation (LTP) and long-term depression (LTD) of the ascending pathways to layers IV and(More)
Long-term depression (LTD) in sensory cortices depends on the activation of NMDA receptors. Here, we report that in visual cortical slices, the induction of LTD (but not long-term potentiation) also requires the activation of receptors coupled to the phospholipase C (PLC) pathway. Using immunolesions in combination with agonists and antagonists, we(More)
Recently, privacy preserving data publishing has received a lot of attention in both research and applications. Most of the previous studies, however, focus on static data sets. In this paper, we study an emerging problem of <i>continuous privacy preserving publishing of data streams</i> which cannot be solved by any straightforward extensions of the(More)
BACKGROUND The standard treatment for patients with multiple myeloma who are not candidates for high-dose therapy is melphalan and prednisone. This phase 3 study compared the use of melphalan and prednisone with or without bortezomib in previously untreated patients with multiple myeloma who were ineligible for high-dose therapy. METHODS We randomly(More)
Endocannabinoids are widely regarded as negative modulators of presynaptic release. Here, we present evidence that in visual cortex endocannabinoids are crucial for the maturation of GABAergic release. We found that between eye opening and puberty, release changes from an immature state with high release probability, short-term depression (STD), and high(More)
This paper proposes a novel generalisation model for selecting characteristic streets in an urban street network. This model retains the central structure of a street network. It relies on a structural representation of a street network using graph principles where vertices represent named streets and links represent street intersections. Based on this(More)
We investigate multiple-input multiple-output (MIMO) eigenmode transmission using statistical channel state information at the transmitter. We consider a general jointly correlated MIMO channel model, which does not require separable spatial correlations at the transmitter and receiver. For this model, we first derive a closed-form tight upper bound for the(More)