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Frontotemporal dementia is a behavioral disorder of insidious onset and variable progression. Clinically, its early features reflect frontal lobe dysfunction characterized by personality change, deterioration in memory and executive functions, and stereotypical and perseverative behaviors. Pathologically, there is degeneration of the neocortex and(More)
Oculopharyngeal muscular dystrophy is a late-onset, autosomally dominant disorder characterized by progressive ptosis, dysphagia, and extremity weakness. Linkage of oculopharyngeal muscular dystrophy to 14q11.2-q13 has been reported in a series of French Canadian families. Haplotype analysis in these data shows a single segregating disease chromosome,(More)
The launch of the Space Shuttle was probably the most visible event of the entire mission cycle. The image of the Main Propulsion System— the Space Shuttle Main Engine and the Solid Rocket Boosters (SRBs)— powering the Orbiter into space captured the attention and the imagination of people around the globe. Even by 2010 standards, these main engines'(More)
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