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We describe the development of an in vitro library selection system (CIS display) that exploits the ability of a DNA replication initiator protein (RepA) to bind exclusively to the template DNA from… Continue Reading
One drawback to the use of peptides as therapeutics has been their susceptibility to proteolysis. Here, we have used an in vitro display technology, CIS display, to enhance the proteolytic resistance… Continue Reading
L'invention concerne un procede de production de banques d'expression in vitro de peptides, et l'isolement de sequences nucleotidiques codant des peptides d'interet, les peptides ou proteines etant… Continue Reading
Although peptides have great potential as therapeutic agents, offering the possibility of chemical synthesis and high specificity for therapeutic targets, their use is often limited by poor stability… Continue Reading