Bill D. Woodward

Learn More
The tolerance model of acute (i.e., wasting) pre-pubescent protein and energy deficits proposes that the immune depression characteristic of these pathologies reflects an intact anti-inflammatory form of immune competence that reduces the risk of autoimmune reactions to catabolically released self antigens. A cornerstone of this proposition is the finding(More)
Inflammatory incompetence is characteristic of acute pediatric protein-energy malnutrition, but its underlying mechanisms remain obscure. Perhaps substantially because the research front lacks the driving force of a scholarly unifying hypothesis, it is adrift and research activity is declining. A body of animal-based research points to a unifying paradigm,(More)
Enormous variability exists among published values for serum corticosterone concentration of mice. Exsanguination of mice is widely used and has been little-tested, but is a likely variable to affect corticosterone concentrations. Exsanguination may impose unrecognized and unnecessary distress on mice used in research. Male and female C57BL/6J mice that(More)
  • 1