Bilel Meddeb

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OBJECTIVE To report the indications and early and late catheter-related complications in a Tunisian unit of paediatric oncology. PATIENTS AND METHODS This prospective study has been performed in a paediatric oncology unit of the Salah Azaïz Institute between 1989 and 2005. It concerns 58 girls and 57 boys with a median age of 7.9 years(4 months to 18(More)
Methods The study was designed as a prospective, double-blind, placebo-controlled, clinical trial and performed in a Tunisian medical surgical intensive care unit. After achieving normovolemia and a mean arterial pressure of at least 65 mmHg, 30 septic shock patients were randomized to one of three intravenous treatment groups: levosimendan 0.2 μg/kg/min (n(More)
Methods Prospective observational study included patients with septic shock admitted to a Tunisian medical -surgical ICU. Each patient was equipped with an arterial and a central venous catheter; patients were also monitored with a pulmonary artery catheter. Treatment for septic shock was standardized according to international recommendations.(More)
INTRODUCTION Mitochondrial dysfunction and consequent cellular energetic failure play a key role in the development of sepsis-related organs failure. Evidence suggests that the pleiotropic effects of levosimendan may positively affect cellular metabolism during septic shock. OBJECTIVES To investigate changes in the concentration of glucose, lactate,(More)
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