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Therapeutic plasma exchange (TPE) has been reported to be a useful adjunct in severe systemic lupus erythematosus (SLE) but paediatric literature continues to be scanty. We hereby present three cases of refractory paediatric SLE (pSLE) with thrombotic thrombocytopenic purpura (TTP), diffuse alveolar haemorrhage (DAH) and crescentic glomerulonephritis which(More)
OBJECTIVES The purpose of this study was to demonstrate quality assurance checks for accuracy of gantry speed and position, dose rate and multileaf collimator (MLC) speed and position for a volumetric modulated arc treatment (VMAT) modality (Synergy S; Elekta, Stockholm, Sweden), and to check that all the necessary variables and parameters were synchronous.(More)
OBJECTIVE This report provides the mathematical commissioning instructions for the evaluation of beam matching between two different linear accelerators. METHODS Test packages were first obtained including an open beam profile, a wedge beam profile and a depth-dose curve, each from a 10×10 cm(2) beam. From these plots, a spatial error (SE) and a(More)
PURPOSE Objective of this study was to evaluate the impact of using flattening filter free (FFF) beam with 0.5 cm multileaf collimator (MLC) leaves over conventional flattened beam with 1 cm leaf width MLC on the treatment plan quality in cranio-spinal irradiation (CSI). METHODS For five medulloblastoma cases (3 males and 2 females), who were previously(More)
PURPOSE To validate and performance test a novel phantom for Volumetric Modulated Arc Therapy MU/dose verification. METHODS A cylindrical phantom was designed using a 2 litter beverage plastic bottle, having useful length of 20.7cm and average diameter is 9.9cm. A hollow plastic tube, having a stopper in the middle, was inserted along the long axis of the(More)
PURPOSE This study was performed to analyze the agreement between optically stimulated luminescence (OSL) nanoDots measured doses and 0.6 cc Farmer type ionization chamber measured doses during total body irradiation (TBI). METHODS In-vivo dose measurements using OSL nanoDots and Farmer chamber were done in a total of twelve patients who received TBI at(More)
PURPOSE Six dimensional positional shifts (translational and rotational) determined by a volumetric imaging system were mathematically combined and incorporated as simple translational shifts and the resultant impact on dose characteristics was studied. METHODS Thirty patients who underwent either single fraction (12 Gy) or five fractions (5 Gy per(More)
PURPOSE This study was designed to evaluate the performance of optically stimulated Luminescence (OSL) nanoDots as in-vivo dosimeter. For the measurements of surface doses as well as scattered plus leakage doses, nanoDots were used during the setup verification as well as during the treatment delivery. METHODS For a total seven patients undergoing(More)
INTRODUCTION The study aimed to investigate the interplay between Monte Carlo Variance (MCV) and fluence smoothing factor (FSF) in volumetric modulated arc therapy treatment planning by using a sample set of complex treatment planning cases and a X-ray Voxel Monte Carlo-based treatment planning system equipped with tools to tune fluence smoothness as well(More)
PURPOSE This study was designed to investigate an appropriate arc span for intact partial Left breast irradiation by VMAT planning. METHODS Four cases of carcinoma left intact breast was chosen randomly for this study. Both medial tangential and left-lateral tangential arc (G20°, G25°, G30°, G35°, G40°) were used having the same length and bilaterally(More)