Bijal Jayakar

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INTRODUCTION Autoinflammatory diseases are characterized by seemingly unprovoked episodes of inflammation, without high titers of autoantibodies or antigen-specific T cells, and derive from genetic variants of the innate immune system. This study characterized a cohort of patients with similar phenotypes and nucleotide oligomerization domain 2 (NOD2) gene(More)
UNLABELLED BACK GROUND AND THE PURPOSE OF STUDY: Sumatriptan succinate is a Serotonin 5- HT1 receptor agonist, used in treatment of migraine. It is absorbed rapidly but incompletely when given orally and undergoes first-pass metabolism, resulting in a low absolute bioavailability of about 15%. The aim of this work was to design mucoadhesive bilayered(More)
The plant Coldenia procumbens Linn. is used commonly in Indian system of medicine for various ailments. The present paper deals with detailed pharmacognosy of the leaf of coldenia procumbens Linn. and includes its Macro/Micro morphological (vein islet, vein termination numbers and stomatal index) anatomical characters, Physico chemical standards such as ash(More)
A simple, rapid and reproducible HPLC method was developed and validated for the estimation of Formoterol Fumarate Rotacaps. Symmetry C8 (4.6×150mm, 5 µ) column, in isocratic mode with mobile phase containing Ammonium Acetate Buffer pH 5.0 and Acetonitrile (80:20) was used. The flow rate was 1.0 ml/min and the analyte was monitored at 254 nm. The retention(More)
  • P Sivakumar, R Sambath Kumar, T Sivakumar, P Perumal, B Jayakar, J K K Nataraja +1 other
  • 2010
Triumfetta rhomboidea (Family: Tiliaceae) is being used in traditional medicine for the treatment of tumors, gonorrhea and leprosy. Ethanol extract of its leaves were subjected for in vitro antioxidant activity using four different methods such as , 1-diphenylpicryl-hydrazyl radical (DPPH), nitric oxide radical and 2, 2'-azino-bis(More)
  • P Palanisamy, B Jayakar, R Margret Chandira, B S Venkateshwarlu, A Pasupathi
  • 2014
The present study deals with the formulation of film coated immediate release tablet of Atorvastatin and sustained release tablet of ezetimibe. Atorvastatin is a selective competitive inhibitor of HMG CoA reductase while Ezetimibe is a lipid lowering drug. Atorvastatin reduces total cholesterol, low density lipoprotein (LDL). HMG CoA reductase catalyzes the(More)
Samadera indica Gaetrn (Simaroubaceae) is claimed to possess various pharmacological activities like antioxidant, antifungal, antitumor, antiviral, and so on, but its taste is bitter. The aim of the present study is to investigate the toxicity of the methanolic extract and to develop suitable herbal formulations of the methanolic extract of Samadera indica,(More)
In the present study methanolic from the leaves of Passiflora edulis for finding potential antibacterial activity. Which were compared with the standard ciprofloxacin 5µg/disc. The invitro antibacterial study efficacy of the methanolic extract was tested against Gram positive bacteria viz. by disc diffusion method. The methanolic extract showed promising(More)
  • M V Kumudhavalli, Margret Chandira, D Sripriya, B Jayakar
  • 2010
The aim of the study is to Synthesis, Method Development, Characterisation and Antimicrobial activities of Ibuprofen lysinate. The following some of the important findings in the present study.Ibuprofen lysinate were synthesized in good yield.Compound exhibited good antimicrobial activity. Percentage recovery of Ibuprofen Lysinate is 99.2% by HPLC .The(More)
The alkali preparation of the root and fresh leaf juice of Moringa oleifera possessed significant dose -depen-dent anti-ulcer activity in experimentally induced acute gastric ulcers with aspirin, the anti-ulcer effect of the alkali preparation of the root seems to be more pronounced than that of the fresh leaf juice. Te anti-ulcer activity of the alkali(More)