Bhupinder P S Khambay

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A homology model of the housefly voltage-gated sodium channel was developed to predict the location of binding sites for the insecticides fenvalerate, a synthetic pyrethroid, and DDT an early generation organochlorine. The model successfully addresses the state-dependent affinity of pyrethroid insecticides, their mechanism of action and the role of(More)
SYNOPSIS A homology model of the housefly voltage-gated sodium channel was developed to predict the location of binding sites for the insecticides fenvalerate, a synthetic pyrethroid and DDT, an early generation organochlorine. The model successfully addresses the state-dependent affinity of pyrethroid insecticides, their mechanisms of action and the role(More)
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