Bheeshma Ravi

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OBJECTIVES To identify a cut point in annual surgeon volume associated with increased risk of complications after primary elective total hip arthroplasty and to quantify any risk identified. DESIGN Propensity score matched cohort study. SETTING Ontario, Canada. PARTICIPANTS 37,881 people who received their first primary total hip arthroplasty during(More)
OBJECTIVE To examine whether total joint arthroplasty of the hip and knee reduces the risk for serious cardiovascular events in patients with moderate-severe osteoarthritis. DESIGN Propensity score matched landmark analysis. SETTING Ontario, Canada. PARTICIPANTS 2200 adults with hip or knee osteoarthritis aged 55 or more at recruitment (1996-98) and(More)
Inhibiting activity of the c-Myb transcription factor attenuates G1 to S phase cell cycle transitions in vascular smooth muscle cells (SMCs) in vitro. To determine the effects of arterial SMC-specific expression of a dominant-negative c-Myb molecule (Myb-Engrailed) on vascular remodeling in vivo, we performed carotid artery wire-denudation in 2 independent(More)
BACKGROUND Because individuals with osteoarthritis (OA) avoid physical activities that exacerbate symptoms, potentially increasing risk for cardiovascular disease (CVD) and death, we assessed the relationship between OA disability and these outcomes. METHODS In a population cohort aged 55+ years with at least moderately severe symptomatic hip and/or knee(More)
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