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The cardioprotective property of hydrogen sulfide (H2S) is recently reported. However, cellular signaling cascades mediated by H2S are largely unclear. This study was undertaken to explore the molecular mechanism of H2S-induced cardioprotection in mouse heart by utilizing in vivo model of cardiac injury. We report here that intraperitoneal administration of(More)
Ritonavir is a HIV protease inhibitor. In addition to its antiviral effect, Ritonavir directly inhibits the insulin-regulated glucose transporter GLUT4 and blocks glucose entry into fat and muscle cells. However, the effect of Ritonavir on cardiac GLUT4 inhibition during myocardial necrosis is not investigated. In the present study, we evaluated the role of(More)
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