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Antioxidant and Hepatoprotective Potentiality of Randia dumetorum Lam. Leaf and Bark via Inhibition of Oxidative Stress and Inflammatory Cytokines
Randia dumetorum Lam. (RD) (Rubiaceae) is traditionally used by some tribes of Assam and Manipur of North East India for the treatment of liver ailments. In this context, to scientifically validate… Expand
Protective Effect of Bioactivity Guided Fractions of Ziziphus jujuba Mill. Root Bark against Hepatic Injury and Chronic Inflammation via Inhibiting Inflammatory Markers and Oxidative Stress
The tribal communities of North Eastern India rely on herbal medicine to cure various disease conditions. Ziziphus jujuba Mill. (Rhamnaceae) is one of such medicinal plants used for curing liver… Expand
Anticancer Activity of Garcinia morella on T-Cell Murine Lymphoma Via Apoptotic Induction
- Bhaswati Choudhury, Raghuram Kandimalla, +4 authors J. Kotoky
- Front. Pharmacol.
- 29 January 2016
Traditional knowledge (TK) based medicines have gained worldwide attention and presently the scientific community is focussing on proper pharmacological validation and identification of lead… Expand
Bioactive Guided Fractions of Annona reticulata L. bark: Protection against Liver Toxicity and Inflammation through Inhibiting Oxidative Stress and Proinflammatory Cytokines
Herbal medicine is popularized worldwide due to its ability to cure the diseases with lesser or no side effects. North Eastern part of India comes under one of the world biodiversity hotspots which… Expand
Bioactive Fraction of Annona reticulata Bark (or) Ziziphus jujuba Root Bark along with Insulin Attenuates Painful Diabetic Neuropathy through Inhibiting NF-κB Inflammatory Cascade
- Raghuram Kandimalla, Suvakanta Dash, +6 authors J. Kotoky
- Biology, Medicine
- Front. Cell. Neurosci.
- 22 March 2017
The present study explains the neuroprotective ability of bioactive fractions of Annona reticulata bark (ARB) and Ziziphus jujuba root bark (ZJ) along with insulin against diabetic neuropathy. By… Expand
Design and development of oxobenzimidazoles as novel androgen receptor antagonists
- Elancheran Ramakrishnan, K. Saravanan, +6 authors J. Kotoky
- Medicinal Chemistry Research
- 21 January 2016
Antiandrogens are a novel class of anticancer agents that inhibit cancer cell proliferation and induce apoptosis in various cell lines. To find the lead compound from the oxobenzimidazole… Expand
Garcinia morella fruit, a promising source of antioxidant and anti-inflammatory agents induces breast cancer cell death via triggering apoptotic pathway.
- Bhaswati Choudhury, Raghuram Kandimalla, E. Ramakrishnan, R. Bharali, J. Kotoky
- Biology, Medicine
- Biomedicine & pharmacotherapy = Biomedecine…
- 1 July 2018
A rapid rise in cancer cases worldwide, especially breast cancer in females, instigates the need for more effective and less side effect causing drugs from natural origin. Thereby, in the present… Expand
Chemical Composition and Anti-Candidiasis Mediated Wound Healing Property of Cymbopogon nardus Essential Oil on Chronic Diabetic Wounds
- Raghuram Kandimalla, Sanjeeb Kalita, Bhaswati Choudhury, Suvakanta Dash, Kasturi Kalita, Jibon Kotoky
- Front. Pharmacol.
- 30 June 2016
Poor wound healing is one of the major complication of diabetic patients which arises due to different factors like hyperglycemia, oxidative stress, vascular insufficiency and microbial infections.… Expand
Fiber from ramie plant (Boehmeria nivea): A novel suture biomaterial.
- Raghuram Kandimalla, Sanjeeb Kalita, +5 authors Jibon Kotoky
- Medicine, Materials Science
- Materials science & engineering. C, Materials for…
- 1 May 2016
The quest for developing an ideal suture material prompted our interest to develop a novel suture with advantageous characters to market available ones. From natural origin only silk, cotton and… Expand
A REVIEW ON ANTI-DIABETIC POTENTIAL OF GENUS SOLANUM (SOLANACEAE)
The Solanum genus ( Solanaceae family) comprised of one thousand five hundred species and most of the members of the genus are widely used as food and traditional medicine. Diabetes mellitus is a… Expand