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Microglial cells, which are resident macrophages of the central nervous system, play important roles in immune responses and pathogenesis. Japanese encephalitis virus (JEV) is a neurotropic virus that infects microglial cells in brain. Several microRNAs including miR-155 and miR-146a play an important role in defining the microglia inflammatory profile. In(More)
Changes in circulating microRNAs (miRNAs) in the cerebrospinal fluid (CSF) have been associated with different neurological diseases. Here, we presented results of a pilot study aimed at determining the feasibility of detecting miRNAs in the CSF of Japanese Encephalitis virus (JEV) infected individuals with acute encephalitis syndrome (AES). We demonstrated(More)
Microglia cells in the brain play essential role during Japanese Encephalitis Virus (JEV) infection and may lead to change in microRNA (miRNA) and mRNA profile. These changes may together control disease outcome. Using Affymetrix microarray platform, we profiled cellular miRNA and mRNA expression at multiple time points during viral infection in human(More)
To achieve a functioning and stable process with high methane production, it is important to create and maintain a beneficial environment for the activity of bacterial consortia of suitable species. Therefore, an experiment has been carried out to isolate methanogenic and nonmethanogenic bacteria from anaerobic biogas system. With this view, a microbial(More)
This paper presents a non-linear dynamic model of a PEM (Proton Exchange Membrane) fuel cell and its simulation in MATLAB. A single cell and three cells stack is fabricated and simulation results obtained are validated experimentally with the dynamic response of the system for change in values of different system parameters. To meet the varying requirements(More)
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