Bharatsingh Bhosale

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CONTEXT Advanced esophageal cancer is aggressive with an expected median survival of 6-7 months. Combination chemotherapy regimens provide effective palliation, but result in substantial toxicity. MATERIALS AND METHODS Retrospective analysis of prospectively collected data of patients with advanced esophageal cancer, not amenable to definitive intent(More)
BACKGROUND Cetuximab based treatment is the recommended chemotherapy for head and neck squamous cell cancers in the palliative setting. However, due to financial constraints, intravenous (IV) chemotherapy without cetuximab is commonly used in lesser developed countries. We believe that oral metronomic chemotherapy may be safer and more effective in this(More)
BACKGROUND Locally advanced and unresectable oral cavity cancers have a poor prognosis. Induction might be beneficial in this setting by reducing tumor bulk and allowing definitive surgery. AIM To analyze the impact of induction chemotherapy on locally advanced, technically unresectable oral cavity cancers. MATERIALS AND METHODS Retrospective analysis(More)
This study studied the coorelation between radiological response to induction chemotherapy and acheivement of pCR or near pCR. It was a retrospective analysis in which all patients who received NACT from 2008 till april 2012 were subjected to inclusion criteria. Coorelation analysis was performed between CR + PR and acheivement of pCR or near pCR. Twenty(More)
Cholangiocarcinoma (CCa) is relatively resistant to chemotherapy as well as radiation therapy, and complete resection is the main curative therapy for these patients. The prognosis for patients with unresectable intrahepatic CCa (iCCa) is extremely poor. A 55-year-old woman presented at our hospital with abdominal pain. After evaluation, she was diagnosed(More)
INTRODUCTION Historically, metastatic renal cell carcinoma (RCC) has had poor prognosis; the outcomes have improved with the introduction of tyrosine-kinase inhibitors, such as sunitinib. There is no reported literature from India on the use of sunitinib in metastatic RCC. We present an analysis of sunitinib at our institute over 4 years. MATERIALS AND(More)
6591 Background: Carmustine, etoposide, ARA-C, melphalan (BEAM) and carmustine, cyclophosphamide, etoposide (CBV) are commonly used high-dose chemotherapy regimens prior to autologous transplantation in patients of non-Hodgkin's (NHL) and Hodgkin's lymphoma (HL) but are associated with significant toxicity. We report the results of lomustine, ARA-C,(More)
CONTEXT Indian febrile neutropenia (FN) data are limited, especially in adult solid tumor patients. AIMS The aim was to study patterns of presentation, source of infection, management and outcome and to evaluate the factors which may correlate with outcome. MATERIALS AND METHODS A retrospective analysis of prospective data of FN patients at a tertiary(More)
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