Bharathi R. Nayak

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Analysis of the Sephacryl S-200 fractionated type IV collagen domains from bovine and human glomerular basement membranes (GBM) and calf anterior lens capsule (ALC) indicated that Asn-linked oligosaccharides are primarily or exclusively localized in the 7 S region, whereas the hydroxylysine-linked Glc alpha 1----2Gal disaccharides (Glc-Gal-Hyl) are present(More)
Proteolytic activity was detected in neem (Azadirachta indica) exudate gum when tested with casein and albumin as substrates. The enzyme activity was separated into two fractions by chromatography on TEAE-cellulose after EDTA treatment. Both the enzyme fractions were fairly stable to high temperatures and wide range of pH conditions. The pH optima were(More)
Serum fucose level was determined in 57 oral cancer patients and 25 normal persons before any treatment was performed. There was a significant rise in these levels in patients with oral cancer, and they correlated well with the clinical stages. This correlation is found to be exceedingly helpful in establishing the presence of and evaluating the extent of(More)
To our knowledge, no study has been undertaken before by any researcher as to the direction of content of the components of serum glycoproteins simultaneously as well as their ratios in oral cancer patients. The aim of the present paper is to establish the direct relationship between fucose and sialic acid levels in the sera of such patients. The(More)
The partial removal of tightly bound Ca2+ from dialysed neem (Azadirachta indica) gum, resulted in the release of a basic protein from a highly anionic polysaccharide-protein complex as evidenced by chromatographic studies on TEAE-cellulose. Complete removal of Ca2+ caused, in addition, the release of a minor heteropolysaccharide which was found in(More)
Background: Suffering from minor ailments is the most frequent episode in childhood experiences. A productive and energetic population cannot grow from unhealthy children who are chronically affected by repeated minor ailments. th Method: An evaluative study using one group pretest posttest design was conducted among 30 school children of 9 class in a(More)
A series of multi-functional hydrogel systems have been designed and synthesized for potential brain implantation to realize controlled and sustained release of Nerve Growth Factor (NGF) for the treatment of Alzheimer’s disease (AD). The systems are three-dimensional crosslinked copolymers composed of a thermo-responsive unit, a hydrolytically degradable(More)
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