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Epstein-Barr virus nuclear antigen 3C interacts with and enhances the stability of the c-Myc oncoprotein.

• Bharat G Bajaj, Masanao Murakami, Qiliang Cai, Subhash C Verma, Ke Lan, Erle S Robertson
• Journal of virology
• 2008

Epstein-Barr virus (EBV) was the first human DNA virus to be associated with cancer. Its oncogenic potential was further demonstrated by its ability to transform primary B lymphocytes in vitro. EBV… (More)

KSHV encoded LANA upregulates Pim-1 and is a substrate for its kinase activity.

• Bharat G Bajaj, Subhash C Verma, Ke Lan, Murray Adrian Cotter, Zenda L Woodman, Erle S Robertson
• Virology
• 2006

Pim kinases are proto-oncogenes that are upregulated in a number of B cell cancers, including Epstein-Barr Virus (EBV) associated Burkitt's lymphoma. They have also been shown to be upregulated in… (More)

Molecular biology of EBV in relationship to AIDS-associated oncogenesis.

• Bharat G Bajaj, Masanao Murakami, Erle S Robertson
• Cancer treatment and research
• 2007

Epstein-Barr virus (EBV) is a gammaherpesvirus of the Lymphocryptovirus genus, which infects greater than 90% of the world's population. Infection is nonsymptomatic in healthy individuals, but has… (More)

Efficient gene transfer to human epidermal keratinocytes on fibronectin: in vitro evidence for transduction of epidermal stem cells.

• Bharat G Bajaj, Pedro Lei, Stelios T Andreadis
• Molecular therapy : the journal of the American…
• 2005

The epidermis is an attractive target for gene therapy because it is easily accessible and has great potential as an ectopic site for protein delivery in vivo. Genetically modified keratinocytes can… (More)

Kaposi's sarcoma herpesvirus-encoded latency-associated nuclear antigen stabilizes intracellular activated Notch by targeting the Sel10 protein.

• Ke Lan, Subhash C Verma, Masanao Murakami, Bharat G Bajaj, Rajeev Kaul, Erle S Robertson
• Proceedings of the National Academy of Sciences…
• 2007

Deregulation of the evolutionarily conserved Notch signaling is highly correlated with oncogenesis. Intracellular activated Notch (ICN) is a protooncogene linked to the transcription activation of a… (More)

Latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus recruits uracil DNA glycosylase 2 at the terminal repeats and is important for latent persistence of the virus.

• Subhash C Verma, Bharat G Bajaj, Qiliang Cai, Huaxin Si, Todd Seelhammer, Erle S Robertson
• Journal of virology
• 2006

Latency-associated nuclear antigen (LANA) of KSHV is expressed in all forms of Kaposi's sarcoma-associated herpesvirus (KSHV)-mediated tumors and is important for TR-mediated replication and… (More)

High efficiencies of gene transfer with immobilized recombinant retrovirus: kinetics and optimization.

• Bharat G Bajaj, Pedro Lei, Stelios T Andreadis
• Biotechnology progress
• 2001

We used a combination of mathematical modeling and experiments to investigate the rate-limiting steps of retroviral transduction on surface-bound fibronectin (FN) and identify the conditions that… (More)

Inhibition of KSHV-infected primary effusion lymphomas in NOD/SCID mice by gamma-secretase inhibitor.

• Ke Lan, Masanao Murakami, +5 authors Erle S Robertson
• Cancer biology & therapy
• 2009

Primary effusion lymphoma (PEL) is a common cancer in AIDS patients closely associated with Kaposi's sarcoma-associated herpesvirus (KSHV). Previously, we showed that KSHV latency associated nuclear… (More)

Retrovirus-associated heparan sulfate mediates immobilization and gene transfer on recombinant fibronectin.

• Pedro Lei, Bharat G Bajaj, Stelios T Andreadis
• Journal of virology
• 2002

Recombinant retroviruses have been shown to bind to fibronectin (FN) and increase the efficiency of gene transfer to a variety of cell types. Despite recent work to optimize gene transfer on… (More)

Isolation of human peripheral blood mononuclear cells (PBMCs).

• Ke Lan, Subhash C Verma, Masanao Murakami, Bharat G Bajaj, Erle S Robertson
• Current protocols in microbiology
• 2007

In this appendix, several basic methods are described for preparation of primary B lymphocyte.

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