Beverly Seavey

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A protein NMR database has been designed and is being implemented. The database is intended to contain solution NMR results from proteins and peptides (larger than 12 residues). A relational database format has been chosen that indexes data by: primary journal citation, molecular species, sequence-related and atom-specific assignments, and experimental(More)
i For my parents, who nurtured my curiosity, and for Natalie, who now piques it. ii ABSTRACT Supervised machine learning is a branch of artificial intelligence concerned with automatically inducing predictive models from labeled data. Such learning approaches are useful for many interesting real-world applications, but particularly shine for tasks involving(More)
Paramecium generates a Ca2+ action potential and can be considered a one-cell animal. Rises in internal [Ca2+] open membrane channels that specifically pass K+, or Na+. Mutational and patch-clamp studies showed that these channels, like enzymes, are activated by Ca(2+)-calmodulin. Viable CaM mutants of Paramecium have altered transmembrane currents and(More)
i For my parents, who nurtured my curiosity, and for Natalie, who now piques it. ii ABSTRACT Supervised machine learning is a branch of artificial intelligence concerned with automatically inducing predictive models from labeled data. Such learning approaches are useful for many interesting real-world applications, but particularly shine for tasks involving(More)
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