Beverley P K Chan

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Radioactive iodine 125 is a low-energy gamma isotope with physical characteristics suitable for irradiation of intraocular tumors. Metal ophthalmic applicators have been designed to shield vital ocular structures while allowing irradiation of the tumor. We compared the radiation effects of iodine 125 and cobalt 60. The Greene melanoma was transplanted into(More)
The center for circadian rhythms in mammals is the suprachiasmatic nucleus (SCN) of the hypothalamus, composed of single cell circadian oscillators driven by a transcriptional/translational feedback loop where clock proteins drive clock gene expression. These genes are expressed in peripheral tissues and several brain areas outside the SCN. It is likely(More)
During the past 8 years, 32 patients with melanoma of the choroid have been treated with cobalt-60 ophthalmic applicators. Excluding three patients lost to follow-up, 24 patients who have now been observed for at least 3 years after treatment form the subject of this study. Each application but two delivered 8,500 to 10,000 rads to the tumour apex. A second(More)
BACKGROUND This study aimed to seek the opinions of academic surgical chairs on minimally invasive surgery (MIS) education for general surgery residents and to identify perceived gaps and trends in educational strategies. METHODS A national survey on attitudes toward MIS was sent to the chairs of departments of surgery and divisions of general surgery(More)
AIM The safety and efficacy of laparoscopic surgery for colon cancer is well established but its uptake in the province has not been previously explored. We report an investigation of the trends of open and laparoscopic surgery for colon cancer in Ontario, Canada. METHOD A retrospective cross-sectional time-series analysis examining population-based rates(More)
Although rare, herniation of the gastrointestinal contents into the pericardium after coronary artery bypass grafting using the right gastroepiploic artery has been previously described. The associated clinical symptoms vary from gastrointestinal obstruction to cardiac tamponade. We report a patient who presented with cardiac tamponade secondary to(More)
AIM The safety and efficacy of laparoscopic surgery for colon cancer have been demonstrated in large, multicentre clinical trials. The study aimed to determine the use of laparoscopic surgery for rectal cancer in Ontario over a 7-year period. METHOD We conducted a retrospective study examining rates of elective rectal cancer surgery among 10.5 million(More)