Bevan Bonhomme

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Collybistin promotes submembrane clustering of gephyrin and is essential for the postsynaptic localization of gephyrin and γ-aminobutyric acid type A (GABA(A)) receptors at GABAergic synapses in hippocampus and amygdala. Four collybistin isoforms are expressed in brain neurons; CB2 and CB3 differ in the C terminus and occur with and without the Src homology(More)
We have found that the γ2 subunit of the GABA(A) receptor (γ2-GABA(A)R) specifically interacts with protocadherin-γC5 (Pcdh-γC5) in the rat brain. The interaction occurs between the large intracellular loop of the γ2-GABA(A)R and the cytoplasmic domain of Pcdh-γC5. In brain extracts, Pcdh-γC5 coimmunoprecipitates with GABA(A)Rs. In cotransfected HEK293(More)
Drosophila class IV multidendritic neurons (green) are shown overlaid with the much simpler dendrite arbors of the class I neurons (magenta). The microtubule severing protein Kat-60L1 is required specifically in the somatodendritic compartment of the class IV neurons late in larval development. Kat-60L1 increases the number of growing microtubules and(More)
An automated system is presented for on-line capture and processing of the analog signal obtained in response to light or X-ray stimulation of isolated rat retina maintained in survival by perfusion. The most important part of the system is a microcomputer Apple II (48 K Europlus) equipped with interface boards. Basic and assembler programs automatically(More)
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