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From 1979-85, 2435 patients with a transient ischaemic attack or minor ischaemic stroke were randomly allocated to receive long term "blind" treatment with aspirin 600 mg twice daily (n = 815), aspirin 300 mg once daily (n = 806) or placebo (n = 814). No patient was lost to follow up. The "intention to treat" comparison included all the serious vascular(More)
It has been reported that nitroglycerin (GTN) tolerance can be prevented by the concurrent administration of hydralazine. Although the mechanism of this effect remains unknown, it is possible that hydralazine modifies counter-regulatory responses to nitrate administration. To address this question, we examined the impact of hydralazine therapy on the(More)
The opinions expressed herein are those of the publisher and do not necessarily reflect the views of the foundation. The methodology and the Discussion Guides were adapted by the RESPOND Project for use in Burkina Faso, Nigeria, Rwanda, and Togo, and for three program assessments conducted by EngenderHealth and the United Nations Population Fund (UNFPA) in(More)
The present study investigated the hypothesis that changes in the frequency of specific behaviors, not assessed by the traditionally employed global measures of locomotor activity, may occur following exposure to cadmium. Two groups of newborn male rat pups were treated orally with either 1.0 mg/kg CdCl2 for 14 days or 10.0 mg/kg CdCl2 for one day followed(More)
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