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We present evidence that native profilin can be purified from cellular extracts of Acanthamoeba, Dictyostelium, and human platelets by affinity chromatography on poly-L-proline agarose. After applying cell extracts and washing the column with 3 M urea, homogeneous profilin is eluted by increasing the urea concentration to 6-8 M. Acanthamoeba profilin-I and(More)
OBJECTIVE To assess the effects of web-based care management on glucose and blood pressure control over 12 months in patients with poorly controlled diabetes. RESEARCH DESIGN AND METHODS For this study, 104 patients with diabetes and HbA(1c) (A1C) > or =9.0% who received their care at a Department of Veterans Affairs medical center were recruited. All(More)
The United States military has been an effective proponent of digital imaging and teleradiology for the past 15 years [1]. A digital imaging network that eliminates the use of x-ray film makes military medicine requirements simpler. X-ray film requirements include storage of new, unexposed films, storage and use of chemicals and water for processing, and(More)
OBJECTIVE Web-based diabetes management can be used to provide frequent interactions between patients and providers and thus result in improved glycemic control. METHODS In a single-center, prospective feasibility study, 16 poorly controlled patients with either type 1 or 2 diabetes mellitus were enrolled to assess the impact of using MyCareTeam, a(More)
One of the advantages that a picture archiving and communications system (PACS) is supposed to provide over a film-based operation is improved performance in retrieving images. Although it seems self-evident that this should be so, this experiment was intended to verify this and to provide some time comparisons for the two methods. The experiment consisted(More)
Using assignments of resonances in the 1H-NMR spectrum of calmodulin obtained by the use of large tryptic fragments of the molecule [Dalgarno, D. C., Klevit, R. E., Levine, B. A., Williams, R. J. P., Dobrowolski, Z., and Drabikowski, W. (1984) Eur. J. Biochem. 138, 281--289], the spectral changes which occur on Ca2+ binding to calmodulin have been examined(More)
The present study was an attempt to examine the role of cue category level (symptom-contingent vs. hypothesized cues) and mode of stimulus presentation (in vivo vs. imaginal) in exposure (flooding) therapy. Sixty-four speech phobics were randomly assigned to one of eight conditions. Exposed to either one of the two cue category conditions, subjects received(More)
The exchange of information between a Radiology Information System (RIS) and a PACS is essential to optimizing the utility of a PACS. Some of the benefits awarded by implementing an interface include a reduction or elimination of repetitious data entry, the availability of more accurate information on the PACS, a reduction in workload for the technologists,(More)
Telemedicine is many things to many people. Only until a few years ago, telemedicine was equated to video teleconferencing between physicians, while nowadays, perhaps the most active area in telemedicine is the store-and-forward model. There is a big shift from private and dedicated modes of communications to connectivity through the Internet. Presented is(More)