Bethy Suryawathy Hernowo

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AIM to evaluate the expression of NF-kB and COX2 in native Indonesians with sporadic colorectal cancer (CRC). METHODS we conducted a matched-pair case-control study by acquiring both CRC and tumor-adjacent normal tissues from the same subjects. CRC patients who underwent surgery at Cipto Mangunkusumo Hospital, Jakarta, or Hasan Sadikin Hospital, Bandung,(More)
INTRODUCTION Testicular damage caused by ischemia reperfusion injury can be determined by malondialdehyde (MDA) expression and grading of the histopathological damage to seminiferous tubules. The aim of this study was to investigate the effect of Tationil Glutathione administration on testicular damage following experimental torsion and detorsion. METHODS(More)
BACKGROUND The pathogenesis of Gestational Trophoblastic Disease (GTD) is not clearly known. OBJECTIVE In this study, immunoexpression of proteins Bcl-2 and Beclin-1 in trophoblastic lesions and normal trophoblastic tissue was conducted to study the mechanism of apoptotic and autophagic cell death that is expected to complete the study of GTD(More)
BACKGROUND Most of the cervical cancer patients, including those with cervical adenocarcinomas, come at advanced stage in the developing world so its mortality is high. Radiotherapy is one of the treatment modality for advanced stage cervical adenocarcinomas, but its efficacy depends on several prognostic factors such as the stage, histopathology, presence(More)
AIM to assess the effect of systemic hypoxia on gastric mucosa and the activation of stress-responsive transcription factors induced by hypoxia. METHODS in this experimental study, rats were allocated to control and experimental groups. The experimental group was divided into subgroups and subjected to hypoxia conditions for 1, 7, 14 or 21 days.(More)
Aim: To obtain clinicopathological characteristics of colorectal cancer among young native Indonesians and to assess MLH1, MSH2, and SMAD4 protein expressions, comparing them with a matched population of colorectal cancer patients aged 60 years old and older. Methods: Medical records of colorectal cancer patients aged 40 years or younger and 60 years or(More)
Hydatidiform moles are considered pre-cancerous lesions of gestational trophoblastic neoplasia and are associated with an aberrant immune response. This preliminary study aimed to evaluate the feasibility of measuring the presence of immune cells as potential prognostic markers for hydatidiform moles. Immunohistochemical staining of FoxP3⁺ regulatory T(More)
Aim: A period of enteral feeding absence is known to cause intestinal atrophy, damaging mucosal barrier and decrease of enterocyte absorption capacity. However, sometimes nothing per oral is inevitable as a part of medical management. During refeeding, damaged intestinal cells are restored. Probiotics are living microorganism, which wields trophic effect on(More)
Endometriosis is an enigmatic disease, with various pathogenesis, uncertain clinical manifestation, invasive and high-risk diagnostic methods, and also various mode of therapy. The endometrium of endometriosis patients shows abnormal protein presentation for protein involved in pathogenesis of endometriosis itself, such as caspases (which is important in(More)