Bethany R Smith

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Neural sites that interact with the suprachiasmatic nuclei (SCN) to generate rhythms of unrestricted feeding remain unknown. We used the targeted toxin, leptin conjugated to saporin (Lep-SAP), to examine the importance of leptin receptor-B (LepR-B)-expressing neurons in the arcuate nucleus (Arc) for generation of circadian feeding rhythms. Rats given Arc(More)
Partitioning locomotor metabolic rates into resting and locomotor components is a common practice that has both basic and applied value. Here, we evaluated the quantitative influence of the specific baseline value subtracted (quiet standing vs. resting metabolic rates) from the gross metabolic rates measured during walking. We quantified resting, standing(More)
We formulated a "one-size-fits-all" model that predicts the energy requirements of level human walking from height, weight, and walking speed. Our three-component model theorizes that the energy expended per kilogram per stride is independent of stature at mechanically equivalent walking speeds. We measured steady-state rates of oxygen uptake of 78 subjects(More)
UlSTer HoSpITal Combination therapy in essential hypertension: effects on insulin action of adding low dose thiazide to aCe inhibitor Background: Concern exists regarding metabolic effects of antihypertensive agents. often more than one agent is required to meet blood pressure targets. angiotensin converting enzyme (aCe) inhibitors, which are at least(More)
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