Beth Goldstein

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The glycine receptor (GlyR) is a ligand-gated ion channel and member of the nicotinic acetylcholine receptor superfamily. Acting as allosteric modulators of receptor function, drugs such as alcohol and volatile anesthetics enhance the function of GlyRs. The actions of these drugs at inhibitory receptors in the brain and spinal cord are thought to produce(More)
This paper describes a process by which anthropologists, computer scientists, and social welfare case managers collaborated to build a stochastic model of welfare advising in Kentucky. In the process of collaboration, the research team rethought the Bayesian network model of Markov decision processes and designed a new knowledge elicitation format. We(More)
Glycine receptor function mediates most inhibitory neurotransmission in the brainstem and spinal cord and is enhanced by alcohols, volatile anesthetics, inhaled drugs of abuse, and endogenous compounds including zinc. Because zinc exists ubiquitously throughout the brain, investigations of its effects on the enhancement of GlyR function by alcohols and(More)
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