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BACKGROUND Adequate lymph node evaluation is required for proper staging of colorectal cancer, and the number of lymph nodes examined is associated with survival. According to current guidelines, the recommended minimum number of lymph nodes examined to ensure adequate sampling is 12. We used data from the National Cancer Institute's Surveillance,(More)
PURPOSE Many patients with unilateral breast cancer choose contralateral prophylactic mastectomy to prevent cancer in the opposite breast. The purpose of our study was to determine the use and trends of contralateral prophylactic mastectomy in the United States. PATIENTS AND METHODS We used the Surveillance, Epidemiology and End Results database to review(More)
BACKGROUND The National Institutes of Health Office of Medical Applications of Research commissioned a structured literature review on the incidence, treatment, and outcomes of ductal carcinoma in situ (DCIS) as a background article for the State of the Science Conference on Diagnosis and Management of DCIS. METHODS Published studies were identified and(More)
BACKGROUND Parathyroid cancer is a rare cause of hyperparathyroidism. The objectives of this study were to determine the patterns of disease, treatment trends, and outcomes among patients with parathyroid cancer by using a population-based data source. METHODS Surveillance, Epidemiology, and End Results (SEER) cancer registry data were used to identify(More)
BACKGROUND Prostate cancer is the second most common cancer in men and has high survivorship, yet little is known about the long-term risk of urinary adverse events (UAEs) after treatment. OBJECTIVE To compare the long-term UAE incidence across treatment and control groups. DESIGN, SETTING, AND PARTICIPANTS Using a matched-cohort design, we identified(More)
BACKGROUND & AIMS Radiation therapy for prostate cancer has been associated with an increased rate of pelvic malignancies, particularly bladder cancer. The association between radiation therapy and colorectal cancer has not been established. METHODS We conducted a retrospective cohort study using Surveillance, Epidemiology, and End Results (SEER) registry(More)
OBJECTIVE To characterize the incidence of vulvar carcinoma in situ and vulvar cancer over time. METHODS We used the Surveillance Epidemiology and End Results database to assess trends in the incidence of vulvar cancer over a 28-year period (1973 through 2000) and determined whether there had been a change in incidence over time. Information collected(More)
BACKGROUND An increase in incidence of ductal carcinoma in situ (DCIS) of the breast has been documented, and concerns regarding overly aggressive treatment have been raised. This study was designed to evaluate the use of surgery and radiation therapy in treating DCIS. METHODS We used the National Cancer Institute's Surveillance, Epidemiology, and End(More)
BACKGROUND Negative margins are associated with reduced risk of ipsilateral breast tumor recurrence (IBTR) for women with ductal carcinoma in situ (DCIS) treated with breast-conserving surgery (BCS). However, there is no consensus about the best minimum margin width. METHODS We searched the PubMed database for studies of DCIS published in English between(More)
BACKGROUND Medicare claims include codes for chemotherapy administration and specific drugs given, and researchers are increasingly using these data to measure the use of chemotherapy. However, the validity and completeness of these data as a source of information has not been established. OBJECTIVES This analysis is intended to assess the utility of the(More)