Beth A. Sproule

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The aim of this paper is to introduce the algorithm proposed in [Fuzzy Sets and System, 2002] and some further modifications. Its applications presented in [ibid; A comparison of five approaches for lithium dose and serum concentration prediction, IFSA-NAFIPS 2001, pp. 104–110] is reviewed as a full collection of its use in phar-macokinetic analysis. First(More)
In this paper a new fuzzy system modeling (FSM) algorithm is introduced as a data analysis and approximate reasoning tool. The performance of the proposed algorithm is tested in two different data sets and compared with some well-known algorithms from the literature. In the comparison two benchmark data sets from the literature, namely the automobile mpg(More)
Anhedonia, a core symptom of Major Depressive Disorder (MDD), is predictive of antidepressant non-response. In contrast to the definition of anhedonia as a "loss of pleasure", neuropsychological studies provide evidence for multiple facets of hedonic function. The aim of the current study was to develop and validate the Dimensional Anhedonia Rating Scale(More)
The resurgence of interest in anhedonia within major depression has been fuelled by clinical trials demonstrating its utility in predicting antidepressant response as well as recent conceptualizations focused on the role and manifestation of anhedonia in depression. Historically, anhedonia has been understood as a "loss of pleasure", yet neuropsychological(More)
This paper provides an overview of research, guidelines, and clinical considerations for the use of medications for chronic pain in the management of patients with an alcohol use disorder. A review of the literature identified randomized controlled trials, epidemiological cohort studies, consensus guidelines, and one systematic review and meta-analysis.(More)
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