Elements of evolutionary computation and molecular biology are combined to design a DNA evolutionary computation. The traditional test problem for evolutionary computation , OneMax problem is addressed. The key feature is the physical separation of DNA strands consistent with OneMax \\tness."
Aspects of Evolutionary Computation, DNA computing, and in vitro evolution are combined in proposed laboratory procedures. Preliminary experimental results are shown. The traditional test problem for Evolutionary Computation known as the OneMax problem is addressed. The preliminary experimental results indicate successful laboratory separation by tness" of… (More)
In vitro DNA amplification methods, such as polymerase chain reaction (PCR), rely on synthetic oligonucleotide primers for initiation of the reaction. In vivo, primers are synthesized on-template by DNA primase. The bacteriophage T7 gene 4 protein (gp4) has both primase and helicase activities. In this study, we report the development of a primase-based… (More)
BACKGROUND In the past decades the rapid growth of molecular diagnostics (based on either traditional PCR or isothermal amplification technologies) meet the demand for fast and accurate testing. Although isothermal amplification technologies have the advantages of low cost requirements for instruments, the further improvement on sensitivity, speed and… (More)