Bertrand Buchs

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Maximizing peak bone mass is advocated as a way to prevent osteoporosis. As a prerequisite to the elaboration of any preventive program aimed at maximizing peak bone mass, it is important to determine how the rate of skeletal growth at clinically relevant sites, such as lumbar spine and femoral neck, proceeds in relation to age and pubertal stages in both(More)
The amount of skeletal mass acquired during adolescence is one of the most important determinants for the risk of postmenopausal and involutional osteoporosis. In both sexes, a large variance in bone mineral density (BMD) and content (BMC) is observed among healthy individuals at the beginning of the third decade. To determine the crucial pubertal years(More)
We investigated the precision of gadolinium 153 dual photon absorptiometry (DPA) and quantitative digital radiography (QDR) bone densitometers by determining in vitro and in vivo coefficients of variation (CV) of bone mineral density (BMD). In vitro, the long-term CV of spine phantom BMD measured weekly for 40 weeks was 1.2% and 0.7% for DPA and QDR,(More)
Dietary protein and/or calorie insufficiencies represent an important problem in elderly patients. The biological and clinical implications, and particularly the influence on bone mass of undernutrition in the elderly, have not been completely defined, although several studies have demonstrated a high prevalence of dietary insufficiencies in patients with a(More)
A para III was found to have a constantly silent CTG. In two fetal blood analyses the pH was normal. During the first few hours post partum the infant had rapidly increasing neurologic disturbances with violent convulsions and coma. As early as on the first day of life the computer tomogram showed extensive, later persistent hypodense zones corresponding to(More)
Tubular reabsorption of calcium (Ca) is becoming recognized as a determinant of malignant hypercalcemia. However, its importance as compared to increased bone resorption has not yet been widely investigated. We determined Ca fluxes of bone resorption and tubular reabsorption in 141 rehydrated patients with hypercalcemia of malignant or benign origin, before(More)
BACKGROUND Care of frail and dependent older adults with multiple chronic conditions is a major challenge for health care systems. The study objective was to test the efficacy of providing integrated care at home to reduce unnecessary hospitalizations, emergency room visits, institutionalization, and mortality in community dwelling frail and dependent older(More)
Bone mineral density (BMD, gr/cm2) and content (BMC, gr) were determined at the levels of the lumbar vertebrae (L2-L4), femoral neck (FN) and midfemoral shaft (FS) using DEX absorptiometry at 1-yr interval in 198 healthy adolescents (98 females, 100 males) aged 9-19 yrs. BMD/ BMC values were related to age, height, weight, pubertal stage and to(More)
Bone mineral density (BMD) was measured by dual photon absorptiometry in the lumbar spine, femoral neck and midfemoral shaft in 209 women and 165 men aged 20 to 98 years recruited among the Geneva population. The prevalence of various factors (life style, calcium intake, body weight) which may be associated with a higher risk of osteoporosis was evaluated.(More)