Bertinho Andrade da Costa

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This paper presents a hand-held microsystem based on new fully integrated magnetoresistive biochips for biomolecular recognition (DNA hybridisation, antibody antigen interaction, etc.). These biochips use magnetic field arraying of magnetically tagged biomolecules and high sensitivity sensors which potentially detect single or few biomolecules.(More)
This paper addresses the local identifiability and sensitivity properties of two classes of Wiener models for the neuromuscular blockade and depth of hypnosis, when drug dose profiles like the ones commonly administered in the clinical practice are used as model inputs. The local parameter identifiability was assessed based on the singular value(More)
A parallel computer architecture and a distributed software platform for automation and control of general anesthesia is proposed in this paper. The system is a prototype research platform, intended to help on the development, simulation and test of new control algorithms for general anesthesia. It must be safe when used in real tests and flexible enough to(More)
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