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OBJECT Navigated transcranial magnetic stimulation (nTMS) is a newly evolving technique. Despite its supposed purpose (for example, preoperative central region mapping), little is known about its accuracy compared with established modalities like direct cortical stimulation (DCS) and functional MR (fMR) imaging. Against this background, the authors(More)
STUDY DESIGN Single-center prospective randomized controlled study. OBJECTIVE To evaluate the accuracy of robot-assisted (RO) implantation of lumbar/sacral pedicle screws in comparison with the freehand (FH) conventional technique. SUMMARY OF BACKGROUND DATA SpineAssist is a miniature robot for the implantation of thoracic, lumbar, and sacral pedicle(More)
OBJECTIVE The goal of this study was to investigate the safety and tolerability of the novel endothelin A (ETA) receptor antagonist clazosentan in patients with subarachnoid hemorrhage (SAH) and its potential to reduce the incidence and severity of cerebral vasospasm following surgical clipping of the aneurysm. METHODS This Phase IIa multicenter study had(More)
OBJECTIVE The purpose of our study was to evaluate the diagnostic accuracy and scan coverage of flat-detector C-arm CT compared with that of biphasic MDCT for depicting malignant hepatic lesions in patients with hypervascular liver tumors before they undergo transarterial chemoembolization (TACE). MATERIALS AND METHODS Fifteen patients with either(More)
STUDY DESIGN An analysis of the incidence of spondylodiscitis after lumbar disc surgery in 1642 patients. In 508 patients no prophylactic antibiotics were given. In 1134 patients a collagenous sponge containing gentamicin was placed in the cleared disc space. OBJECTIVES To report the incidence of postoperative spondylodiscitis in cases in which no(More)
PURPOSE To evaluate the effect of automatic bone and plaque removal on image quality and grading of steno-occlusive lesions in patients undergoing dual energy CT angiography (CTA) of lower extremity. MATERIALS AND METHODS Dual energy (DE) runoff CTA was performed in 50 patients using the following parameters: collimation 2 x 32 x 0.6; tube potentials, 80(More)
BACKGROUND Navigated transcranial magnetic stimulation (nTMS) is increasingly used in presurgical brain mapping. Preoperative nTMS results correlate well with direct cortical stimulation (DCS) data in the identification of the primary motor cortex. Repetitive nTMS can also be used for mapping of speech-sensitive cortical areas. OBJECTIVE The current(More)
BACKGROUND Aneurysmal subarachnoid haemorrhage (SAH) is a devastating disease with high mortality and disability. The data from large longitudinal studies on health-related quality of life (HRQoL) in patients with SAH are limited. The objective was to investigate HRQoL in patients after SAH and to identify predictors of HRQoL. METHODS 113 patients with(More)
Subsequent to admission after aneurysmal subarachnoid haemorrhage (SAH), 120 patients (74 women and 46 men) underwent microsurgical clipping of a total of 158 cerebral aneurysms within 96 hours after the bleed. Their mean age was 46 (20–91) years. Computed tomography (CT) findings were graded according to the modified Fisher scale and all patients had daily(More)
OBJECTIVE This study assessed the feasibility and safety of percutaneous posterior pedicle screw fixation for instabilities of the thoracic and lumbar spine, using standard instruments designed for the open approach and fluoroscopy. METHODS All patients who underwent percutaneous posterior pedicle screw fixation of the thoracic and lumbar spine were(More)