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STUDY DESIGN It has been previously demonstrated that sustained nonpatterned electric stimulation of the posterior lumbar spinal cord from the epidural space can induce stepping-like movements in subjects with chronic, complete spinal cord injury. In the present paper, we explore physiologically related components of electromyographic (EMG) recordings(More)
We provide evidence that the human spinal cord is able to respond to external afferent input and to generate a sustained extension of the lower extremities when isolated from brain control. The present study demonstrates that sustained, nonpatterned electrical stimulation of the lumbosacral cord—applied at a frequency in the range of 5–15 Hz and a strength(More)
Individual electric and geometric characteristics of neural substructures can have surprising effects on artificially controlled neural signaling. A rule of thumb approved for the stimulation of long peripheral axons may not hold when the central nervous system is involved. This is demonstrated here with a comparison of results from the electrically(More)
  • B Jilge
  • 1993
The nursing rhythms of 14 rabbit does and the activity of 18 litters from birth to days 14-16 were monitored continuously, as were the circadian rhythms of different behavioral functions of 10 young rabbits from weaning until day 380 of life. The does gave birth 2 hr, 26 min +/- 2 hr, 8 min after lights-on in a light-dark cycle (LD 12:12). The first nursing(More)
Electrical stimulation of the lumbar cord at distinct frequency ranges has been shown to evoke either rhythmical, step-like movements (25–50 Hz) or a sustained extension (5–15 Hz) of the paralysed lower limbs in complete spinal cord injured subjects. Frequency-dependent activation of previously “silent” spinal pathways was suggested to contribute to the(More)
Five different physiological functions of the rabbit (hard faeces and urine excretion, food and water intake and locomotor activity) were registered during LD 12:12 and during continuous light conditions (LL). (1) In LD 12:12 a strong synchronization of the five parameters existed. The minima of all functions consistently occurred during the hours of light.(More)
The free-running circadian rhythms of five behavioral functions of the rabbit were masked by unsignalled restricted food access (RF). The rhythms were reorganized immediately, a large part of events being assembled around the end of food availability. In addition to masking a slower process of entrainment was running: a component of anticipatory activity(More)
The direction of temporary phase shifts depends on the timing of the light signal in the dark period (1800-0600). Delays predominated following signals between 2100 and 2400, while advances tended, even more uniformly, to follow signals given between 0100 and 0400. In one animal the caecotrophy rhythm split into 2 components after a light signal at 0400,(More)
Three main concerns underlie this review: 1) The need to draw together the widely dispersed information available on the circadian biology of the rabbit. Although the rabbit is a classic laboratory mammal, this extensive body of information is often overlooked by chronobiologists, and despite several advantages of this species. In terms of its general(More)
The term competence, as it first appeared in the European guidelines, was rather poorly defined and hence resulted in some confusion. It was FELASA'sinitiative in working with the various competence categories, which made the concept clear and comprehensive. According to FELASAthere are four competence categories (FELASA1995): Category A-Animal technicians(More)