Bernhard Irrgang

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Tissue engineering using human cells and tissue has one of the greatest scientific and economical potential in the coming years. There are public concerns during the ongoing discussion about future trends in life sciences and if ethic boundaries might be respected sufficiently in the course of striving for industrial profit and scientific knowledge. Until(More)
We introduce a method of constructing a forcing along a simplified (κ, 1)-morass such that the forcing satisfies the κ-chain condition. Alternatively, this may be seen as a method to thin out a larger forcing to get a chain condition. As an application, we construct a ccc forcing that adds an ω2-Suslin tree. Related methods are Shelah’s historic forcing and(More)
Infection with the hepatitis C virus (HCV) commonly causes persistent disease, which may lead to cirrhosis and hepatocellular carcinoma. The pathogenesis of HCV infection is not well understood. It is most likely that both viral and host factors contribute to HCV persistence. This review focuses on the host's immune response to HCV in an attempt to present(More)
Research with human tissue offers the possibility not only of improving preclinical pharmaceutical research and safety assessment, but also of the substitution of some animal experiments. Surgically removed human tissue is discarded after pathological evaluation. This tissue would be of enormous value for research, especially in the pharmaceutical branch,(More)
Twenty-three diarylcarbenium ions and 38 pi-systems (arenes, alkenes, allyl silanes and stannanes, silyl enol ethers, silyl ketene acetals, and enamines) have been defined as basis sets for establishing general reactivity scales for electrophiles and nucleophiles. The rate constants of 209 combinations of these benzhydrylium ions and pi-nucleophiles, 85 of(More)
It is consistent that there exists a sequence 〈Xα | α < ω3〉 of subsets Xα ⊆ ω1 such that Xβ − Xα is finite and Xα − Xβ is uncountable for all β < α < ω3. Such a sequence is added by a ccc forcing which is constructed along a simplified (ω1, 2)-morass. The idea of the proof is to use a finite support iteration of countable forcings which is not linear but(More)