Bernhard Goebel

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Finding the causal genetic regions underlying complex traits is one of the main aims in human genetics. In the context of complex diseases, which are believed to be controlled by multiple contributing loci of largely unknown effect and position, it is especially important to develop general yet sensitive methods for gene mapping. We discuss the use of(More)
In this paper, the distribution of mutual information between two discrete random variables is approximated by means of a second-order Taylor series expansion. Approximative expressions for the distribution of mutual information (MI) between independent random variables, conditional MI between conditionally independent variables, and MI between (weakly)(More)
The mutual information between a complex-valued channel input and its complex-valued output is decomposed into four parts based on polar coordinates: an amplitude term, a phase term, and two mixed terms. Numerical results for the additive white Gaussian noise (AWGN) channel with various inputs show that, at high signal-to-noise ratio (SNR), the amplitude(More)
We derive the channel capacity of CO-OFDM systems limited by FWM. Simulations confirm that Peak-to-Average-Power-Ratio reduction techniques are suitable for FWM mitigation. These techniques can utilize the decreased capacity to significantly increase the system reach. c © 2008 Optical Society of America OCIS codes: (060.2330) Fiber optics communications;(More)
This study defined age stereotypes as attitudes toward specific age groups which differ significantly from those held toward other age groups. Characteristics ascribed by 72 Caucasian female student nurses to five different age groups (children, adolescents, young adults, middle-aged adults, and old adults) were identified and compared. Repeated measures(More)
The DNA sequencing efforts of the past years together with rapid progress in sequencing technology have generated a huge amount of sequence data available in public molecular databases. This recent development makes it statistically feasible to apply universal concepts from Shannon’s information theory to problems in molecular biology, e.g to use mutual(More)
In coherent optical OFDM systems, the large peak-to-average power ratio (PAPR) gives rise to signal impairments through the nonlinearity of modulator and fiber. We review the most prominent PAPR reduction techniques that have been proposed for mitigating the impairments with regard to their reduction capability, computational complexity and redundancy.(More)
In fiber-optic systems with multiple channels or subcarriers, any three channels create new signal components through the nonlinear process of Four-Wave-Mixing (FWM). For the first time, to our best knowledge, we calculate the number of these products for each frequency. The results can be useful for nonlinear system analysis of multiplexed fiber-optic(More)
This study was an investigation of age preferences of older adults (ages 61 to 89 years) for individuals with whom a relationship may potentially affect life satisfaction. Initially, nine older persons sorted photographs into categories by age and attractiveness. Photographs of young, middle-aged, and old adults (ages from early 20s to early 70s) controlled(More)