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A transient increase in intracellular free calcium is believed to be the signal responsible for the stimulation of the egg metabolism at fertilization and the resumption of the cell cycle. We have studied how the polyphosphoinositides (PPI) turn over at fertilization in sea urchin eggs, in order to determine the relationship between the metabolism of these(More)
We investigated the role of follicle cells during meiosis reinitiation in the oocytes of Patella vulgata. Germinal vesicle breakdown, chromosome condensation, and metaphase-1 spindle formation were artificially induced by treating oocytes with 10 mM NH4Cl. By following the accumulation of 32PO4 and [3H]inositol in polyphosphoinositides (PPI) and by(More)
The metabolism of polyphosphoinositides (PPI) has been investigated during the meiosis reinitiation of the oocytes of a prosobranch mollusk, the limpet Patella vulgata. Meiosis reinitiation which leads to germinal vesicle breakdown (GVBD) and metaphase-1 spindle formation was artificially induced by treating the prophase-blocked oocytes with 10 mM NH4Cl, pH(More)
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