Bernd Möller

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According to published data, 60% of hepatitis C virus (HCV)-infected patients in Croatia have HCV genotype 1. The second most common genotype is 3a (36%). Standard treatment regimen for patients with chronic hepatitis C is a combination of pegylated interferon alfa (2a or 2b) with ribavirin, in duration guided by genotype: patients with genotype 1 are(More)
In the paper a new concept of modeling uncertainty is presented, based on the theory of fuzzy random variables. By this means, a super-ordinate uncertainty model is made available which includes the models developed so far, based on random variables and fuzzy variables as special cases. The fuzzy random variables are accounted for as input values in the(More)
UNLABELLED Although sofosbuvir has been approved for patients with genotypes 2/3 (G2/3), many parts of the world still consider pegylated Interferon alpha (P) and ribavirin (R) as standard of care for G2/3. Patients with rapid virological response (RVR) show response rates >80%. However, SVR (sustained virological response) in non-RVR patients is not(More)
  • Henrik Lund, Frede Hvelplund, Poul Alberg Østergaard, Bernd Möller, Brian Vad Mathiesen, Anders N Andersen +9 others
  • 2010
Acknowledgement This study is part of the research project Coherent Energy and Environmental System Analysis (CEESA), partly financed by the Danish Council for Strategic Research. The rest has been financed by the companies and institutions of the authors. This study has been initiated and conducted solely on the initiative of the authors and involve no(More)
Uncertain input parameters may result from "fuzziness", "randomness" or "fuzzy randomness". With the use of fuzzy set theory, uncertain input parameters may be described mathematically as fuzzy variables or fuzzy random variables and may be integrated into safety assessment analysis. With the aid of-discretization involving the multiple solution of special(More)
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