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Service-Oriented Computing (SOC) is a new computing paradigm that utilizes services as the basic constructs to support the development of rapid, low-cost and easy composition of distributed applications even in heterogeneous environments. The visionary promise of Service-Oriented Computing is a world of cooperating services where application components are(More)
Peer-oriented computing is an attempt to weave interconnected machines into the fabric of the Internet. Service-oriented computing (exemplified by web-services), on the other hand, is an attempt to provide a loosely coupled paradigm for distributed processing. In this paper we present an event-notification based architecture and formal framework towards(More)
BACKGROUND The presence of disseminated tumor cells (DTCs) in bone marrow of patients with early breast cancer (EBC) has been correlated with increased risk of metastatic disease or locoregional relapse. Zoledronic acid (ZOL) treatment has reduced DTCs in the bone marrow of patients with EBC in several studies. This controlled study sought to confirm these(More)
7 Abstract The international standard IEC 61131-3, which supports Brad Cox' concept of " Software-ICs " 9 for industrial control programming, is increasingly being used in safety-related application domains. They include safety-instrumented functions, such as burner management, emergency shut-11 down and gas leak detection, but also complex automation(More)
The software architect is concerned with both functional and non-functional design. An important task in functional design is the adaptation of a component's provided interface for use by other components. In non-functional analysis the focus is rather on the prediction and reasoning about reliability and performance properties. We present a method for(More)
Web based learning provides an unprecedented flexibility and convenience to both learners and instructors. However, it also creates a great number of lonely learners. Hence, there is an urgent need for finding an efficient way to help the learners share their learning experiences and exchange their learning materials during the learning process. This paper(More)