Bernardino Fernández-Calvo

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There is currently a need to develop tools to identify patients with mild AD and mild cognitive impairment (MCI). We determined the validity and reliability of a brief, easily administered cognitive screening battery consisting of fusion of two well-known brief tests (Mini-Mental Status Examination [MMSE] and Clock Drawing Test [CDT]) (Mini-clock) to(More)
en la familia sobre aspectos sociosanitarios relacio-nados con el enfermo [19]; y c) ayuda a reducir cos-tes sanitarios asociados al uso de servicios a domi-cilio y especializados [8]. Idealmente, un test de cribado debe ser bien acep-tado por los pacientes y evaluar, de una manera sen-cilla, breve y psicométricamente eficaz, diferentes dominios cognitivos(More)
OBJECTIVE The aim of this paper was to compare the performance of a group of patients with early Alzheimer's disease (EAD) against a control group of healthy control (HC) subjects in the Clock Drawing Test (CDT), i.e. verbal command versus copying of a clock model presented to the subject. PATIENTS AND METHODS The authors have studied 140 subjects; 70(More)
The study aims to assess the efficacy of the Big Brain Academy (BBA), a computerized cognitive training program (CT) based on video games, compared to the Integrated Psychostimulation Program (IPP), a classical CT tool for patients with Alzheimer's disease (AD). A total of 45 patients with AD at the mild stage were randomly assigned to three experimental(More)
Clinical heterogeneity is one of the characteristics of Alzheimer's disease (AD). Hence, the atypical frontal or dysexecutive presentation is becoming increasingly well-known, although the underlying factors are still unknown. In this study, the neuropsychological performance of two groups of patients with AD (frontal variant-ADfv-and typical-TAD) were(More)
INTRODUCTION Depression is one of the most common neuropsychiatric disorders in Alzheimer's disease (AD). AIM To evaluate whether depression exacerbates verbal and non-verbal memory impairment in early AD patients. SUBJECTS AND METHODS The study compared the performance of 23 patients who received a diagnosis of AD, with or without depression, 15(More)
BACKGROUND Traditional treatment for motor impairment after stroke includes medication and physical rehabilitation. The transcranial direct current stimulation associated with a standard physical therapy program may be an effective therapeutic alternative for these patients. METHODS This study is a sham-controlled, double-blind, randomized clinical trial(More)
OBJECTIVES This research retrospectively analyzed the effect of education on cognitive interventions carried out in patients with mild Alzheimer's disease (AD). METHODS The total sample consisted of 75 patients with mild AD receiving treatment with cholinesterase inhibitors. The participants were divided into two groups: cognitive intervention (IG; n=45)(More)
The 37-item version of the Mini-Mental State Examination (MMSE-37) is an extended version of the original test for individuals with low education, which was adapted for different cultures. Despite its favorable psychometric properties, there is a lack of normative data for this instrument. We provide normative data for the MMSE-37 stratified by age, sex,(More)
Early separation of mild cognitive impairment (MCI) from normal aging and mild cases of dementia remains a challenge, especially in the general population. We aimed to analyze the diagnostic accuracy of a brief neuropsychological battery (BNB) in dementia and MCI cases from the Neurological Disorders in Central Spain (NEDICES) population-based cohort study.(More)