Bernard Rousseau

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OBJECTIVES We describe a method for eliciting phonation in an in vivo rabbit preparation using low-frequency, bipolar pulsed stimulation of the cricothyroid muscles with airflow delivered to the glottis. METHODS Ten New Zealand White breeder rabbits weighing 3 to 5 kg were used in this study. The cricothyroid muscles were isolated bilaterally, and(More)
OBJECTIVES/HYPOTHESIS Our laboratory has developed an in vivo rabbit model to investigate the effects of phonation on expression and turnover of the vocal fold extracellular matrix. As a logical outgrowth of this research to include phonotrauma in the present study, we investigated the hypothesis that an increase in airflow rate delivered to the glottis(More)
Because the vocal folds undergo repeated trauma during continuous cycles of vibration, the epithelium is routinely susceptible to damage during phonation. Excessive and prolonged vibration exposure is considered a significant predisposing factor in the development of vocal fold pathology. The purpose of the present study was to quantify the extent of(More)
Three-dimensional fluid-structure interaction (FSI) involving large deformations of flexible bodies is common in biological systems, but accurate and efficient numerical approaches for modeling such systems are still scarce. In this work, we report a successful case of combining an existing immersed-boundary flow solver with a nonlinear finite-element(More)
When developing high-fidelity computational model of vocal fold vibration for voice production of individuals, one would run into typical issues of unknown model parameters and model validation of individual-specific characteristics of phonation. In the current study, the evoked rabbit phonation is adopted to explore some of these issues. In particular, the(More)
OBJECTIVES/HYPOTHESIS The purpose of this study was to use nonlinear dynamic analysis methods such as phase space portraits and correlation dimension (D2) as well as descriptive spectrographic analyses to characterize acoustic signals produced during evoked rabbit phonation. METHODS Seventeen New Zealand white breeder rabbits were used to perform the(More)
Human vocal folds experience flow-induced vibrations during phonation. In previous computational models, the vocal fold dynamics has been treated with linear elasticity theory in which both the strain and the displacement of the tissue are assumed to be infinitesimal (referred to as model I). The effect of the nonlinear strain, or geometric nonlinearity,(More)
The purpose of this study was to identify the presence and characteristics of the distribution patterns of elastic fibers in a 15-week-old C57BL/6J mouse vocal fold, to confirm the presence and distribution of collagen fibers, and to describe potential gender differences in staining patterns, with the aim of further developing the mouse model for use in(More)
Introduction: The treatment of bilateral vocal fold paralysis (BVFP) includes cordotomy, suture lateralization, arytenoidectomy, or tracheostomy. Laryngeal pacing, a novel method of treating BVFP, works by direct electrical stimulation of the Posterior Cricoarytenoid Muscle (PCA), thereby resulting in abduction of the vocal fold Methods: A total of seven(More)
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