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BACKGROUND Understanding socio-demographic inequalities in stage at diagnosis can inform priorities for cancer control. PATIENTS AND METHODS We analysed data on the stage at diagnosis of East of England patients diagnosed with any of 10 common cancers, 2006-2010. Stage information was available on 88 657 of 98 942 tumours (89.6%). RESULTS Substantial(More)
For the past three years, the ACM Publications Board has been developing its vision for the future of publication in the electronic age and a program to achieve it. I am pleased to present that plan here. We envisage a diminishing role for print journals and exciting new programs around an ACM digital library. The plan raises important policy questions(More)
The ACM Computing Classification System (CCS), which for 20 years has served as the primary and most generally used system for the classification and indexing of the published literature of computing, has been substantially revised to reflect the greatly changed nature of computing. In this article, the revision committee reports on its work, describes the(More)
BACKGROUND Stage at diagnosis is a key predictor of overall cancer outcome. For the first time, stage completeness is high enough for robust analysis for the whole of England. METHODS We analysed data from the National Cancer Registration Service's (NCRS) Cancer Analysis System on persons diagnosed with breast, colorectal, lung, prostate or ovarian(More)
BACKGROUND Understanding variation in stage at diagnosis can inform interventions to improve the timeliness of diagnosis for patients with different cancers and characteristics. METHODS We analysed population-based data on 17,836 and 13,286 East of England residents diagnosed with (female) breast and lung cancer during 2006-2009, with stage information on(More)
The widespread distribution of enzymes classed as semicarbazide-sensitive amine oxidases (SSAO enzymes) throughout a very wide range of eukaryotic as well as prokaryotic organisms encourages the aspirations of those who wish to demonstrate physiological, pathological or pharmacological importance. Such enzymes are found in several tissues of mammals, both(More)
Socioeconomic issues associated with the delivery of online content and services are as critical to success as sound technological implementation, if indeed not more so. ACM distinguished itself in its advanced planning for its digital library by paying close attention to three such issues: changing patterns in scholarly behavior; the functioning of(More)
A CM has CoMpleted a major update of its Computing Classification System (CCS), which has served as the de facto standard for classifying the computing literature since 1964. NYU professor Zvi Kedem served as Editor-in-Chief of this special CCS Update Project, leading a group of 120 computing specialists— a third of whom are ACM Fellows a —to collaborate(More)
Patients dying from primary intracranial malignancy are a potential source of organs for transplantation. However, a perceived risk of tumor transfer to the organ recipient has limited their use. We evaluated the risk of tumor transmission by reviewing the incidence in patients transplanted in the UK. Information from the UK Transplant Registry was combined(More)
—A new type of " active curation system " is becoming prevalent in computer science that provides executable access to artifacts and experiments behind published results and enables their reuse. These systems allow changing and repeating experiments to understand how an innovation behaves in conditions beyond the ones described in a paper. Active curation(More)