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Differential Regulation of Human Eosinophil IL-3, IL-5, and GM-CSF Receptor α-Chain Expression by Cytokines: IL-3, IL-5, and GM-CSF Down-Regulate IL-5 Receptor α Expression with Loss of IL-5
Our recent data suggested that tissue eosinophils may be relatively insensitive to anti-IL-5 treatment. We examined cross-regulation and functional consequences of modulation of eosinophil cytokineExpand
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Autocrine growth control in human carcinoma cells in vitro
This project examined methodologies used to establish primary cell cultures from non-small cell lung carcinoma (NSCLC) tumours. The objective was to enhance the in vitro proliferative potential ofExpand