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Although numerous methods to register brains of different individuals have been proposed, no work has been done, as far as we know, to evaluate and objectively compare the performances of different nonrigid (or elastic) registration methods on the same database of subjects. In this paper, we propose an evaluation framework, based on global and local(More)
This paper describes an interactive system for the semantic annotation of brain magnetic resonance images. The system uses both a numerical atlas and symbolic knowledge of brain anatomical structures depicted using the Semantic Web standards. This knowledge is combined with graphical data, automatically extracted from the images by imaging tools. The(More)
Medical image simulation produces virtual images from software representations of imaging devices and virtual object models representing the human body. Object models consist of the geometry of the objects (e.g. organs, tissues, pathological structures, etc.) and of their physical parameters used for the simulation. The diversity of this information makes(More)
OBJECT The authors present the use of cortical sulci, segmented from magnetic resonance (MR) imaging, and functional data from functional (f)MR imaging and magnetoencephalography (MEG) in the image-guided surgical management of lesions adjacent to the sensorimotor cortex. METHODS In an initial set of 11 patients, sulci near lesions were automatically(More)
The goal of the NeuroBase project is to facilitate collaborative research in neuroimaging through a federated system based on semantic web technologies. The cornerstone and focus of this paper is the design of a common semantic model providing a unified view on all data and tools to be shared. For this purpose, we built a multi-layered and multi-components(More)
An important issue is to know whether Web ontology languages, meet the expected requirements of expressiveness and reasoning. This paper aims at contributing to this question in evaluating and comparing several languages. After describing the needs of a Semantic Web in medicine, it analyses Protégé and DAML+OIL primitives on a concrete medical ontology, the(More)
Among the basal ganglia nuclei, the subthalamic nucleus (STN) is considered to play a major role in output modulation. The STN represents a relay of the motor cortico-basal ganglia-thalamo-cortical circuit and has become the standard surgical target for treating Parkinson's patients with long-term motor fluctuations and dyskinesia. But chronic bilateral(More)
Within the scope of three-dimensional brain imaging, we propose an interindividual fusion scheme to register functional activations according to anatomical cortical structures, the sulci. This paper is based on the assumption that an important part of functional intersubject variability is encoded in anatomical variability. The aim of this paper is(More)
Quantitative evaluation of brain MRI/SPECT fusion methods for normal and in particular pathological datasets is difficult, due to the frequent lack of relevant ground truth. We propose a methodology to generate MRI and SPECT datasets dedicated to the evaluation of MRI/SPECT fusion methods and illustrate the method when dealing with ictal SPECT. The method(More)