Bernard Eclancher

Learn More
A linear relationship between the proton relaxation rates and the fraction of deoxyhemoglobin of circulating whole blood (fHb) has been established in vitro at 4.7 T. These results have been interpreted on the basis of the additivity of relaxation rates. The slope of the lines of transverse relaxation rates (R2) versus fHb was found to increase with(More)
The most widely used free radicals for dynamic nuclear polarization (DNP) experiments or related Overhauser imaging are nitroxides. The DNP parameters in biological fluids were measured in order to provide guidelines for the design of new nitroxides, adapted to the biological applications of DNP. Eighteen nitroxides were studied at a concentration of 1 mM.(More)
A simple way of making elastic tubes using a mechanical lathe for precise control of the wall thickness is proposed in this study. These tubes are particularly useful for modeling properties of large arteries. Tubes with different geometric parameters and hence different elastic behavior have been made with a silicon elastomer (Rhodorsil RTV 1556). They(More)
The purpose of this study was to perform serial texture analysis of brain MRI of cuprizone-treated mice for the assessment of regional demyelination and remyelination. Cuprizone-fed mice undergo a brain demyelination process. This process was followed over 56 days by MRI in the olfactory bulbs, cerebellum, putamen and brain stem. The texture of T2-weighted(More)
Magnetic resonance images of rat brain were analyzed by texture analysis in order to study the effects of a nociceptive stimulation (formalin test) under propofol deep anesthesia. Changes of the texture in different cerebral brain areas acquired before and after stimulation were checked. Our statistical analysis of texture shows that these changes were(More)
This study describes quantitatively the effect of O2 on the dynamic nuclear polarization (DNP) of water protons. It is shown theoretically how DNP enhancement is altered by the paramagnetism of O2. The nonlinear effect of oxygen on the enhancement factor has been approximated by a first order expression that provides accurate predictions of the experimental(More)
Chronically hypoxic crayfish,Astacus pallipes, were exposed to transient inhalations of hyperoxic water, and the ventilation was followed cycle by cycle. Fast polarographic probes recorded changes of the partial pressure of oxygen,P O 2, of the inspired and expired water, of the hemolymph in the pericardial sinus, and of the water at the base of first and(More)
Injection of NaCN or lobeline into the ventral aorta of the trout or carp provokes hyperventilation and bradycardia within 5 seconds, responses which are the weaker the higher the oxygen tension of the ambient water. The reactions, precisely similar to the chemoreflexes of higher vertebrates, suggest that these fish also possess arterial chemoreceptors.
Blood has been considered as a simplified tissue model, both physiologically and physically consisting in two compartments, extra-cellular and intra-cellular. In the physiologic condition (300 mOsm), the relaxation rates of red cell suspensions in saline increased linearly with the hematocrit in the range 0–0.80 according to Fullerton's model of fast proton(More)
Endorem®, a suspension of superparamagnetic iron oxide dextran nanoparticles (NP), have been injected intravenously to healthy anesthetized rats for the purpose of contrast enhancement of brain in gradient-echo imaging at 200 MHz. Not only gray and white matter but also particular regions of the cerebrospinal fluid (CSF) were contrasted in sagittal and(More)