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  • Liming Zhou, Xueheng Cheng, Bernard A. Connolly, Mark J Dickman, P J Hurd, David P. Hornby
  • Chemistry, Medicine
  • Journal of molecular biology
  • 2002 (First Publication: 1 August 2002)
  • Mechanism-based inhibitors of enzymes, which mimic reactive intermediates in the reaction pathway, have been deployed extensively in the analysis of metabolic pathways and as candidate drugs. TheExpand
  • M A Greagg, Mark J. Fogg, George N. Panayotou, Simon J. Evans, Bernard A. Connolly, Laurence H. Pearl
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1999 (First Publication: 3 August 1999)
  • Deamination of cytosine to uracil is the most common promutagenic change in DNA, and it is greatly increased at the elevated growth temperatures of hyperthermophilic archaea. If not repaired toExpand
  • Sabra L. Reid, D Parry, Hong Hong Liu, Bernard A. Connolly
  • Chemistry, Medicine
  • Biochemistry
  • 2001 (First Publication: 1 February 2001)
  • Oligonucleotides labeled with hexachlorofluorescein (hex) have enabled the interaction of the restriction endonuclease EcoRV with DNA to be evaluated using fluorescence anisotropy. The sensitivity ofExpand